Journal article
Utility and utilization of transabdominal ultrasound in pediatric patients with acute recurrent or chronic pancreatitis
Journal of pediatric gastroenterology and nutrition, Vol.82(2), pp.557-565
02/2026
DOI: 10.1002/jpn3.70303
PMID: 41318969
Abstract
Transabdominal ultrasound (TAUS) is frequently utilized in pediatric acute pancreatitis, but less is known about its use in acute recurrent (ARP) or chronic pancreatitis (CP). Our aim was to describe TAUS utilization and findings from the largest multicenter cohort of pediatric ARP and CP, the International Study Group of Pediatric Pancreatitis: In Search for a CuRE-2 (INSPPIRE-2).
Demographic and imaging data from physician questionnaires were obtained for patients with available TAUS data. Utilization and findings were compared between ARP and CP groups. Kappa statistics were used to compare agreement of TAUS to computed tomography (CT), magnetic resonance imaging/cholangiopancreatography (MRI/MRCP), endoscopic ultrasound (EUS), and endoscopic retrograde cholangiopancreatography (ERCP) for CP findings.
There were 895 patients (460 ARP, 435 CP) included with 2531 TAUS examinations. Mean number of TAUS per year was similar between CP and ARP patients (0.90 vs. 0.90, p = 0.97). The pancreas was well visualized in 65% of examinations (60% ARP vs. 68% CP, p ≤ 0.001). TAUS and CT demonstrated the most consistent agreement among other modalities with kappa values ranging from 0 to 0.66 with substantial agreement for pancreatic duct irregularities (ĸ = 0.62) and moderate agreement for calcifications (ĸ = 0.57). Agreement between other modalities and TAUS was generally lower and diminished closer to CP diagnosis date.
This is the largest report of TAUS findings in children with ARP or CP. TAUS has several benefits in the initial or emergent evaluation of ARP including availability and tolerance. The ability of TAUS to screen for progression of disease requires further study.
Details
- Title: Subtitle
- Utility and utilization of transabdominal ultrasound in pediatric patients with acute recurrent or chronic pancreatitis
- Creators
- Nicholas Norris - The University of Texas Southwestern Medical CenterDavid Troendle - The University of Texas Southwestern Medical CenterMichael Wilschanski - Hebrew University of JerusalemFuchenchu Wang - The University of Texas MD Anderson Cancer CenterGretchen A Cress - University of IowaMaisam A Abu-El-Haija - Cincinnati Children's Hospital Medical CenterAnkur Chugh - Medical College of WisconsinReuven Zev Cohen - Emory UniversityElissa M Downs - University of Minnesota Children's HospitalDouglas S Fishman - Baylor College of MedicineCheryl E Gariepy - Nationwide Children's HospitalMatthew J Giefer - Ochsner Medical CenterTanja Y Gonska - Hospital for Sick ChildrenAmit S Grover - Boston Children's HospitalSohail Z Husain - Stanford UniversityDouglas Lindblad - Children's Hospital of PittsburghQuin Y Liu - Cedars-Sinai Medical CenterAsim Maqbool - Children's Hospital of PhiladelphiaJacob A Mark - Children's Hospital ColoradoMegha S Mehta - The University of Texas Southwestern Medical CenterBrian A McFerron - Indiana University School of MedicineVeronique D Morinville - McGill UniversityKenneth Ng - Johns Hopkins Children's CenterRobert A Noel - Baylor College of MedicineChee Y Ooi - UNSW SydneyEmily R Perito - University of California, San FranciscoZachary M Sellers - Stanford UniversityAndrew T Trout - Cincinnati Children's Hospital Medical CenterYuhua Zheng - Children's Hospital of Los AngelesYing Yuan - The University of Texas MD Anderson Cancer CenterMark E Lowe - Washington University in St. LouisAliye Uc - University of IowaConsortium for the Study of Chronic Pancreatitis, Diabetes and Pancreatic Cancer
- Resource Type
- Journal article
- Publication Details
- Journal of pediatric gastroenterology and nutrition, Vol.82(2), pp.557-565
- DOI
- 10.1002/jpn3.70303
- PMID
- 41318969
- NLM abbreviation
- J Pediatr Gastroenterol Nutr
- ISSN
- 1536-4801
- eISSN
- 1536-4801
- Publisher
- Wiley
- Grant note
- R01 DK118752 / NIDDK NIH HHS 2U01 DK108328 / National Institute of Diabetes and Digestive and Kidney Diseases and the National Cancer Institute of the National Institutes of Health 2U01 DK108334 / National Institute of Diabetes and Digestive and Kidney Diseases and the National Cancer Institute of the National Institutes of Health
- Language
- English
- Electronic publication date
- 11/29/2025
- Date published
- 02/2026
- Academic Unit
- Stead Family Department of Pediatrics; Gastroenterology, Hepatology, Pancreatology, and Nutrition
- Record Identifier
- 9985089031002771
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