Journal article
Utility of rapid onsite evaluation of touch imprint cytology from endoscopic and cholangioscopic forceps biopsy sampling (with video)
Gastrointestinal endoscopy, Vol.89(2), pp.340-344
02/2019
DOI: 10.1016/j.gie.2018.08.050
PMID: 30193904
Abstract
Rapid onsite evaluation of touch imprint cytology (ROSE-TIC) is a simple and rapid method used for the diagnosis of benign and malignant lesions. We evaluated the diagnostic accuracy of ROSE-TIC for advanced intestinal luminal and indeterminate pancreatobiliary lesions during endoscopy.
This is a retrospective descriptive study of patients who underwent endoscopy or ERCP between January 1, 2014 and December 31, 2016. It included patients who were referred for the treatment of intestinal luminal lesions or evaluation of indeterminate pancreatobiliary lesions. The slides were prepared by gently touching the specimen onto a glass slide and were examined under the microscope. The main outcome measure was to determine the diagnostic accuracy of ROSE-TIC by comparing the onsite cytology findings with the corresponding off-site histologic diagnosis.
All 222 patients (106 pancreatobiliary and 116 GI lesions) had a prior benign diagnosis of intestinal luminal lesions or indeterminate diagnosis of pancreatobiliary lesions. The overall sensitivity, specificity, positive predictive value, negative predictive value, and diagnostic accuracy of ROSE-TIC were 97%, 85%, 83%, 97.2%, and 90%, respectively. The accuracy varied with the site of the biopsy sample. The accuracy was lowest for upper GI tract, where it was 85.2% but was 95% for lower GI tract lesions.
By establishing a rapid onsite diagnosis, ROSE-TIC expedites decision-making on patient management. Prospective studies are needed to confirm these preliminary findings.
Details
- Title: Subtitle
- Utility of rapid onsite evaluation of touch imprint cytology from endoscopic and cholangioscopic forceps biopsy sampling (with video)
- Creators
- Saeed Ali - Department of Internal Medicine, Florida Hospital, Orlando, Florida, USARobert H Hawes - Center for Interventional Endoscopy, Florida Hospital, Orlando, Florida, USAKambiz Kadkhodayan - Center for Interventional Endoscopy, Florida Hospital, Orlando, Florida, USAEhsan Rafiq - Center for Interventional Endoscopy, Florida Hospital, Orlando, Florida, USAUdayakumar Navaneethan - Center for Interventional Endoscopy, Florida Hospital, Orlando, Florida, USAJi Y Bang - Center for Interventional Endoscopy, Florida Hospital, Orlando, Florida, USAShyam Varadarajulu - Center for Interventional Endoscopy, Florida Hospital, Orlando, Florida, USAMuhammad K Hasan - Center for Interventional Endoscopy, Florida Hospital, Orlando, Florida, USA
- Resource Type
- Journal article
- Publication Details
- Gastrointestinal endoscopy, Vol.89(2), pp.340-344
- DOI
- 10.1016/j.gie.2018.08.050
- PMID
- 30193904
- ISSN
- 0016-5107
- eISSN
- 1097-6779
- Language
- English
- Date published
- 02/2019
- Academic Unit
- General Internal Medicine; Internal Medicine
- Record Identifier
- 9984094401002771
Metrics
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