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VASCULAR COMPLICATIONS IN PEDIATRIC PANCREATITIS: A CASE SERIES
Journal article   Open access   Peer reviewed

VASCULAR COMPLICATIONS IN PEDIATRIC PANCREATITIS: A CASE SERIES

Chinenye R Dike, Gretchen Cress, Douglas S. Fishman, Tanja Gonska, Chee Y. Ooi, Emily R. Perito, David Troendle, Cynthia M. Tsai, Mark E. Lowe and Aliye Uc
Journal of pediatric gastroenterology and nutrition, Vol.73(4), pp.e94-e97
10/01/2021
DOI: 10.1097/MPG.0000000000003218
PMCID: PMC8455425
PMID: 34224489
url
https://www.ncbi.nlm.nih.gov/pmc/articles/8455425View
Open Access

Abstract

We reviewed INSPPIRE ( IN ternational S tudy Group of P ediatric P ancreatitis: I n Search for a Cu RE ) database for splanchnic venous thrombosis or arterial pseudoaneurysms to determine the incidence, risk factors and outcomes of peripancreatic vascular complications in children with acute recurrent pancreatitis (ARP) or chronic pancreatitis (CP). Of 410 children with diagnostic imaging studies, vascular complications were reported in 5 (1.2%); 2 had ARP, 3 CP. The vascular events were reported during moderately severe or severe acute pancreatitis (AP) in 4, mild AP in 1. Venous thrombosis occurred in 4, arterial pseudoaneurysm (left gastric artery) in 1. 2 patients with venous thrombosis were treated with anticoagulant, 1 achieved recanalization (splenic vein). In 2 patients who did not receive anticoagulants, 1 re-canalized. No adverse effects were observed with anticoagulants. The child with pseudoaneurysm underwent aneurysmal coiling. Anti-coagulants appear to be safe in children with acute pancreatitis, their long-term benefit needs to be further investigated.
 acute recurrent pancreatitis chronic pancreatitis, thrombosis, splenic vein, portal vein pediatric pancreatitis

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