Vaginal Toxic Shock Reaction Triggering Desquamative Inflammatory Vaginitis

Nigel Pereira; Thomas D Edlind; Patrick M Schlievert; Paul Nyirjesy

doi:10.1097/LGT.0b013e3182656991

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Vaginal Toxic Shock Reaction Triggering Desquamative Inflammatory Vaginitis

Journal article

Open access

Peer reviewed

Vaginal Toxic Shock Reaction Triggering Desquamative Inflammatory Vaginitis

Nigel Pereira, Thomas D Edlind, Patrick M Schlievert and Paul Nyirjesy

Journal of lower genital tract disease, Vol.17(1), pp.88-91

01/2013

DOI: 10.1097/LGT.0b013e3182656991

PMCID: PMC3522853

PMID: 23222054

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https://www.ncbi.nlm.nih.gov/pmc/articles/3522853View

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Abstract

Objective The study aimed to report 2 cases of desquamative inflammatory vaginitis associated with toxic shock syndrome toxin 1 (TSST-1)–producing Staphylococcus aureus strains. Materials and Methods Case report of 2 patients, 1 with an acute and 1 with a chronic presentation, diagnosed with desquamative inflammatory vaginitis on the basis of clinical findings and wet mount microscopy. Pretreatment and posttreatment vaginal bacterial and yeast cultures were obtained. Results Pretreatment vaginal bacterial cultures from both patients grew TSST-1–producing S. aureus. Subsequent vaginal bacterial culture results after oral antibiotic therapy were negative. Conclusions Desquamative inflammatory vaginitis may be triggered through TSST-1–mediated vaginal toxic shock reaction.

Desquamative inflammatory vaginitis

toxic shock syndrome toxin

toxic shock syndrome

Vaginitis

Details

Title: Subtitle: Vaginal Toxic Shock Reaction Triggering Desquamative Inflammatory Vaginitis
Creators: Nigel Pereira - Department of Microbiology, University of Iowa, Carver College of Medicine, Iowa City, IA
Thomas D Edlind - Department of Microbiology, University of Iowa, Carver College of Medicine, Iowa City, IA
Patrick M Schlievert - Department of Microbiology, University of Iowa, Carver College of Medicine, Iowa City, IA
Paul Nyirjesy - Department of Microbiology, University of Iowa, Carver College of Medicine, Iowa City, IA
Resource Type: Journal article
Publication Details: Journal of lower genital tract disease, Vol.17(1), pp.88-91
DOI: 10.1097/LGT.0b013e3182656991
PMID: 23222054
PMCID: PMC3522853
NLM abbreviation: J Low Genit Tract Dis
ISSN: 1089-2591
eISSN: 1526-0976
Grant note: R01 AI074283 || AI / National Institute of Allergy and Infectious Diseases Extramural Activities : NIAID U54 AI057153 || AI / National Institute of Allergy and Infectious Diseases Extramural Activities : NIAID
Language: English
Date published: 01/2013
Academic Unit: Microbiology and Immunology; Internal Medicine
Record Identifier: 9984001219402771

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