Journal article
Validation of a Crisis Standards of Care Model for Prioritization of Limited Resources During the Coronavirus Disease 2019 Crisis in an Urban, Safety-Net, Academic Medical Center
Critical care medicine, Vol.49(10), pp.1739-1748
10/01/2021
DOI: 10.1097/CCM.0000000000005155
PMCID: PMC8439631
PMID: 34115635
Abstract
The coronavirus disease 2019 pandemic has overwhelmed healthcare resources even in wealthy nations, necessitating rationing of limited resources without previously established crisis standards of care protocols. In Massachusetts, triage guidelines were designed based on acute illness and chronic life-limiting conditions. In this study, we sought to retrospectively validate this protocol to cohorts of critically ill patients from our hospital.
We applied our hospital-adopted guidelines, which defined severe and major chronic conditions as those associated with a greater than 50% likelihood of 1- and 5-year mortality, respectively, to a critically ill patient population. We investigated mortality for the same intervals.
An urban safety-net hospital ICU.
All adults hospitalized during April of 2015 and April 2019 identified through a clinical database search.
None.
Of 365 admitted patients, 15.89% had one or more defined chronic life-limiting conditions. These patients had higher 1-year (46.55% vs 13.68%; p < 0.01) and 5-year (50.00% vs 17.22%; p < 0.01) mortality rates than those without underlying conditions. Irrespective of classification of disease severity, patients with metastatic cancer, congestive heart failure, end-stage renal disease, and neurodegenerative disease had greater than 50% 1-year mortality, whereas patients with chronic lung disease and cirrhosis had less than 50% 1-year mortality. Observed 1- and 5-year mortality for cirrhosis, heart failure, and metastatic cancer were more variable when subdivided into severe and major categories.
Patients with major and severe chronic medical conditions overall had 46.55% and 50.00% mortality at 1 and 5 years, respectively. However, mortality varied between conditions. Our findings appear to support a crisis standards protocol which focuses on acute illness severity and only considers underlying conditions carrying a greater than 50% predicted likelihood of 1-year mortality. Modifications to the chronic lung disease, congestive heart failure, and cirrhosis criteria should be refined if they are to be included in future models.
Details
- Title: Subtitle
- Validation of a Crisis Standards of Care Model for Prioritization of Limited Resources During the Coronavirus Disease 2019 Crisis in an Urban, Safety-Net, Academic Medical Center
- Creators
- Albert Nadjarian - Boston Medical CenterJessica LeClair - Boston UniversityTaylor F Mahoney - Boston UniversityEric H Awtry - Boston UniversityJasvinder S Bhatia - Boston UniversityLisa B Caruso - Boston Medical CenterAlexis Clay - Boston Medical CenterDavid Greer - Boston UniversityKaran S Hingorani - Boston Medical CenterL F B Horta - Boston Medical CenterMichel Ibrahim - Boston Medical CenterMichael H Ieong - Boston UniversityThea James - Boston UniversityMatthew H Kulke - Boston UniversityRemington Lim - Boston UniversityRobert C Lowe - Boston UniversityJames M Moses - Boston UniversityJaime Murphy - Boston UniversityAla Nozari - Boston UniversityAnuj D Patel - Boston Medical CenterBrent Silver - Boston Medical CenterArthur C Theodore - Boston UniversityRyan Shufei Wang - Boston Medical CenterEllen Weinstein - National Patient Safety FoundationStephen A Wilson - Boston Medical CenterAnna M Cervantes-Arslanian - Boston Medical Center
- Resource Type
- Journal article
- Publication Details
- Critical care medicine, Vol.49(10), pp.1739-1748
- DOI
- 10.1097/CCM.0000000000005155
- PMID
- 34115635
- PMCID
- PMC8439631
- NLM abbreviation
- Crit Care Med
- ISSN
- 0090-3493
- eISSN
- 1530-0293
- Grant note
- UL1 TR001863 / NCATS NIH HHS
- Language
- English
- Date published
- 10/01/2021
- Academic Unit
- Internal Medicine
- Record Identifier
- 9984694743902771
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