Validation of tablet-based evaluation of color fundus images

Mark Christopher; Daniela C Moga; Stephen R Russell; James C Folk; Todd Scheetz; Michael D Abràmoff

doi:10.1097/IAE.0b013e3182483361

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Validation of tablet-based evaluation of color fundus images

Journal article

Peer reviewed

Validation of tablet-based evaluation of color fundus images

Mark Christopher, Daniela C Moga, Stephen R Russell, James C Folk, Todd Scheetz and Michael D Abràmoff

Retina (Philadelphia, Pa.), Vol.32(8), pp.1629-1635

09/2012

DOI: 10.1097/IAE.0b013e3182483361

PMCID: PMC3396716

PMID: 22495326

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https://www.ncbi.nlm.nih.gov/pmc/articles/3396716View

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Abstract

To compare diabetic retinopathy (DR) referral recommendations made by viewing fundus images using a tablet computer with those made using a standard desktop display. A tablet computer (iPad) and a desktop computer with a high-definition color display were compared. For each platform, 2 retinal specialists independently rated 1,200 color fundus images from patients at risk for DR using an annotation program Truthseeker. The specialists determined whether each image had referable DR and also how urgently each patient should be referred for medical examination. Graders viewed and rated the randomly presented images independently and were masked to their ratings on the alternative platform. Tablet-based and desktop display-based referral ratings were compared using cross-platform intraobserver kappa as the primary outcome measure. Additionally, interobserver kappa, sensitivity, specificity, and area under the receiver operating characteristic were determined. A high level of cross-platform intraobserver agreement was found for the DR referral ratings between the platforms (κ = 0.778) and for the 2 graders (κ = 0.812). Interobserver agreement was similar for the 2 platforms (κ = 0.544 and κ = 0.625 for tablet and desktop, respectively). The tablet-based ratings achieved a sensitivity of 0.848, a specificity of 0.987, and an area under the receiver operating characteristic of 0.950 compared with desktop display-based ratings. In this pilot study, tablet-based rating of color fundus images for subjects at risk for DR was consistent with desktop display-based rating. These results indicate that tablet computers can be reliably used for clinical evaluation of fundus images for DR.

Reproducibility of Results

Area Under Curve

Diagnostic Imaging - instrumentation

Humans

Computers, Handheld - standards

Diagnostic Imaging - standards

Diabetic Retinopathy - diagnosis

Diagnostic Techniques, Ophthalmological - standards

Pilot Projects

Diagnostic Techniques, Ophthalmological - instrumentation

Sensitivity and Specificity

ROC Curve

Referral and Consultation

Fundus Oculi

Retina - pathology

Observer Variation

Details

Title: Subtitle: Validation of tablet-based evaluation of color fundus images
Creators: Mark Christopher - Department of Biomedical Engineering, College of Public Health, University of Iowa, Iowa City, Iowa 52242, USA. mark-christopher@uiowa.edu
Daniela C Moga
Stephen R Russell
James C Folk
Todd Scheetz
Michael D Abràmoff
Resource Type: Journal article
Publication Details: Retina (Philadelphia, Pa.), Vol.32(8), pp.1629-1635
DOI: 10.1097/IAE.0b013e3182483361
PMID: 22495326
PMCID: PMC3396716
NLM abbreviation: Retina
ISSN: 1539-2864
eISSN: 1539-2864
Publisher: United States
Grant note: EY017066 / NEI NIH HHS R01 EY017066 / NEI NIH HHS UL1RR024979 / NCRR NIH HHS R01 EY019112 / NEI NIH HHS UL1 RR024979 / NCRR NIH HHS R01 EY018853 / NEI NIH HHS UL1 RR024979-04 / NCRR NIH HHS
Language: English
Date published: 09/2012
Academic Unit: Roy J. Carver Department of Biomedical Engineering; Electrical and Computer Engineering; Ophthalmology and Visual Sciences
Record Identifier: 9983806370902771

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