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Validation of the University of Washington quality of life questionnaires for head and neck cancer patients in India
Journal article   Open access   Peer reviewed

Validation of the University of Washington quality of life questionnaires for head and neck cancer patients in India

A. K. D'cruz, B. Yueh, A. K. Das, J. A. McDowell, D. A. Chaukar and A. W. Ernest
Indian journal of cancer, Vol.44(4), pp.147-154
10/01/2007
DOI: 10.4103/0019-509X.39377
PMID: 18322357
url
https://doi.org/10.4103/0019-509X.39377View
Published (Version of record) Open Access

Abstract

Quality of life (QOL) is a multidimensional construct capturing the subjective wellbeing of patients in physical, emotional, functional and social domains. Available work on post treatment QOL have only been made in western literature and less in Indian literature. Aims : To translate the UWQOL into both Hindi and Marathi and psychometrically validate the translation in HandN cancer patients in Indian population. Settings and Design : A prospective study was done at the Tata Memorial Hospital for patients who were treated for H and N cancers. Materials and Methods : 147 patients were enrolled from January to April 2005. The study was carried out in two phases. Patients were given translated versions of the UWQOL and EORTC QOL questionnaires preoperatively, 15 days postoperatively and then three months postoperatively. Results : Both the Hindi and Marathi translations had strong internal consistency (Cronbach's alpha=0.7971 and 0.7839). UWQOL composite scores correlated well with the global questions on overall QOL in both the Hindi (r=0.69) and Marathi (r=0.66) translations and also with Tstage. QOL scores were worse three months postoperatively than preoperatively and for patients undergoing surgery that violated the mucosa. A strong correlations was observed (r>0.50) between all similar domains on the UWQOL and EORTC HandN35 except the saliva item on the Marathi translation, where r<0.50, but Pvalues were significant. Conclusions : The Marathi and Hindi versions of the UWQOL appear to be valid and reliable instruments for assessing the QOL in Indian population and will be a vital tool for achieving greater insight into the short and the long term QOL.
 Quality of Life Head and neck cancer Questionnaires Validity

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