Journal article
Validity of the 12-item World Health Organization Disability Assessment Schedule 2.0 (WHODAS 2.0) in individuals with Huntington disease (HD)
Quality of life research, Vol.24(8), pp.1963-1971
08/01/2015
DOI: 10.1007/s11136-015-0930-x
PMCID: PMC4497948
PMID: 25636661
Abstract
The reliability and construct validity of the 12-item World Health Organization Disability Assessment Schedule 2.0 (WHODAS 2.0) were examined in individuals with Huntington disease (HD).
We examined factor structure (confirmatory factor analysis), internal consistency reliability (Cronbach's alpha), floor and ceiling effects, convergent validity (Pearson correlations), and known-groups validity (multivariate analysis).
Results of a confirmatory factor analysis replicated the six-factor latent model that reflects the six separate scales within the WHODAS 2.0 (understanding and communicating; getting around; self-care; getting along with others; life activities; participation). Cronbach's alpha for the scale was 0.94, suggesting good internal consistency reliability. The WHODAS demonstrated a ceiling effect for 19.5 % of participants; there were no floor effects. There was evidence for convergent validity; the WHODAS demonstrated moderate significant correlations with other general measures of health-related quality of life (HRQOL; i.e., RAND-12, EQ5D). Multivariate analyses indicated that late-stage HD participants indicated poorer HRQOL than both early-stage HD and prodromal HD participants for all HRQOL measures.
Findings provide support for both the reliability and validity of the WHODAS 2.0 in individuals with HD.
Details
- Title: Subtitle
- Validity of the 12-item World Health Organization Disability Assessment Schedule 2.0 (WHODAS 2.0) in individuals with Huntington disease (HD)
- Creators
- Noelle E. Carlozzi - University of Michigan–Ann ArborAnna L. Kratz - University of Michigan–Ann ArborNancy R. Downing - University of IowaSiera Goodnight - University of Michigan–Ann ArborJennifer A. Miner - University of Michigan–Ann ArborNicholas Migliore - University of Michigan–Ann ArborJane S. Paulsen - University of Iowa
- Resource Type
- Journal article
- Publication Details
- Quality of life research, Vol.24(8), pp.1963-1971
- Publisher
- Springer Nature
- DOI
- 10.1007/s11136-015-0930-x
- PMID
- 25636661
- PMCID
- PMC4497948
- ISSN
- 0962-9343
- eISSN
- 1573-2649
- Number of pages
- 9
- Grant note
- 1R01NS077946; 5R01NS040068 / National Institutes of Health (NIH), National Institute of Neurological Disorders and Stroke; United States Department of Health & Human Services; National Institutes of Health (NIH) - USA; NIH National Institute of Neurological Disorders & Stroke (NINDS) NIH; United States Department of Health & Human Services; National Institutes of Health (NIH) - USA UL1TR000114 / National Center for Advancing Translational Sciences; United States Department of Health & Human Services; National Institutes of Health (NIH) - USA; NIH National Center for Advancing Translational Sciences (NCATS) CHDI Foundation awards
- Language
- English
- Date published
- 08/01/2015
- Academic Unit
- Psychiatry; Psychological and Brain Sciences
- Record Identifier
- 9984383923202771
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