Variability of performance status assessment between patients with hematologic malignancies and their physicians

Alexis D. Leal; Cristine Allmer; Matthew J. Maurer; Tait D. Shanafelt; James R. Cerhan; Brian K. Link; Carrie A. Thompson

doi:10.1080/10428194.2017.1347930

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Variability of performance status assessment between patients with hematologic malignancies and their physicians

Journal article

Open access

Peer reviewed

Variability of performance status assessment between patients with hematologic malignancies and their physicians

Alexis D. Leal, Cristine Allmer, Matthew J. Maurer, Tait D. Shanafelt, James R. Cerhan, Brian K. Link and Carrie A. Thompson

Leukemia & lymphoma, Vol.59(3), pp.695-701

03/04/2018

DOI: 10.1080/10428194.2017.1347930

PMCID: PMC5901757

PMID: 28718335

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https://www.ncbi.nlm.nih.gov/pmc/articles/5901757View

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Abstract

This study was conducted to determine the incidence of inter-observer variability in Eastern Cooperative Oncology Group (ECOG) performance status (PS) rating between patients with leukemia and lymphoma and their physicians. ECOG PS was assessed at diagnosis by patients and their physicians and stratified by disease subtype, gender, age, disease stage and education. Association between patient- and physician-rated PS and overall survival (OS) was stratified by subtype and prognostic risk score. Overall, 65% of patients and physicians rated PS the same. Age, disease stage and disease subtype were significant predictors of PS disagreement. PS was a significant predictor of OS irrespective of assessment by patients or physicians across all subtypes except those with Hodgkin lymphoma. These findings suggest the need for physicians to better communicate with patients when determining PS, as PS is a strong predictor of survival and is critical in treatment decisions, including determining fitness for cancer treatment.

cancer

inter-observer agreement

leukemia

lymphoma

overall survival

Performance status

Details

Title: Subtitle: Variability of performance status assessment between patients with hematologic malignancies and their physicians
Creators: Alexis D. Leal - a Department of Internal Medicine , Mayo Clinic , Rochester , MN , USA.
Cristine Allmer - Mayo Clinic in Florida
Matthew J. Maurer - Mayo Clinic
Tait D. Shanafelt - c Division of Hematology/Department of Internal Medicine , Mayo Clinic , Rochester , MN , USA.
James R. Cerhan - Mayo Clinic
Brian K. Link - University of Iowa
Carrie A. Thompson - Mayo Clinic
Resource Type: Journal article
Publication Details: Leukemia & lymphoma, Vol.59(3), pp.695-701
DOI: 10.1080/10428194.2017.1347930
PMID: 28718335
PMCID: PMC5901757
NLM abbreviation: Leuk Lymphoma
ISSN: 1042-8194
eISSN: 1029-2403
Publisher: Taylor & Francis
Grant note: University of Iowa
Language: English
Date published: 03/04/2018
Academic Unit: Hematology, Oncology, and Blood & Marrow Transplantation; Epidemiology; Internal Medicine
Record Identifier: 9984359581602771

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