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Variation in Severe Acute Respiratory Syndrome Coronavirus 2 Bioaerosol Production in Exhaled Breath
Journal article   Open access   Peer reviewed

Variation in Severe Acute Respiratory Syndrome Coronavirus 2 Bioaerosol Production in Exhaled Breath

Renu Verma, Eugene Kim, Nicholas Degner, Katharine S Walter, Upinder Singh and Jason R Andrews
Open forum infectious diseases, Vol.9(1), p.ofab600
01/01/2022
DOI: 10.1093/ofid/ofab600
PMCID: PMC8753034
PMID: 35028332
url
https://doi.org/10.1093/ofid/ofab600View
Published (Version of record) Open Access

Abstract

We developed a simple, noninvasive mask sampling method to quantify and sequence severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) from exhaled breath. We found substantial variation between individuals in SARS-CoV-2 copies exhaled over a 15-minute period, which moderately correlated with nasal swab viral load. Talking was associated with a median of 2 log10 greater exhaled viral copies. Exposure varies substantially between individuals but may be risk stratified by nasal swab viral load and whether the exposure involved conversation.
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