Journal article
Variation in susceptibility of bloodstream isolates of Candida glabrata to fluconazole according to patient age and geographic location in the United States in 2001 to 2007
Journal of clinical microbiology, Vol.47(10), pp.3185-3190
10/2009
DOI: 10.1128/JCM.00946-09
PMCID: PMC2756923
PMID: 19656983
Abstract
We examined the susceptibilities to fluconazole of 642 bloodstream infection (BSI) isolates of Candida glabrata and grouped the isolates by patient age and geographic location within the United States. Susceptibility of C. glabrata to fluconazole was lowest in the northeast region (46%) and was highest in the west (76%). The frequencies of isolation and of fluconazole resistance among C. glabrata BSI isolates were higher in the present study (years 2001 to 2007) than in a previous study conducted from 1992 to 2001. Whereas the frequency of C. glabrata increased with patient age, the rate of fluconazole resistance declined. The oldest age group (> or = 80 years) had the highest proportion of BSI isolates that were C. glabrata (32%) and the lowest rate of fluconazole resistance (5%).
Details
- Title: Subtitle
- Variation in susceptibility of bloodstream isolates of Candida glabrata to fluconazole according to patient age and geographic location in the United States in 2001 to 2007
- Creators
- M A Pfaller - Medical Microbiology Division, Department of Pathology, University of Iowa College of Medicine, Iowa City, IA 52242, USA. michael-pfaller@uiowa.eduS A MesserR J HollisL BoykenS TendolkarJ KroegerD J Diekema
- Resource Type
- Journal article
- Publication Details
- Journal of clinical microbiology, Vol.47(10), pp.3185-3190
- Publisher
- United States
- DOI
- 10.1128/JCM.00946-09
- PMID
- 19656983
- PMCID
- PMC2756923
- ISSN
- 0095-1137
- eISSN
- 1098-660X
- Language
- English
- Date published
- 10/2009
- Academic Unit
- Infectious Diseases; Epidemiology; Pathology; Internal Medicine
- Record Identifier
- 9983986260602771
Metrics
13 Record Views