Journal article
Variation of Interstitial Glucose Measurements Assessed by Continuous Glucose Monitors in Healthy, Nondiabetic Individuals
Diabetes care, Vol.33(6), pp.1297-1299
06/01/2010
DOI: 10.2337/dc09-1971
PMCID: PMC2875442
PMID: 20215454
Abstract
OBJECTIVE - To characterize glucose levels during daily living using continuous glucose monitors (CGMs) in nondiabetic
RESEARCH DESIGN AND METHODS - Seventy-four healthy children, adolescents, and adults aged 9-65 years with normal glucose tolerance used a blinded CGM device for 3 to 7 days.
RESULTS - Sensor glucose concentrations were 71-120 mg/dl for 91% of the day. Sensor values were <= 60 or >140 mg/dl for only 0.2% and 0.4% of the clay, respectively. Sensor glucose concentrations were slightly higher in children than adults (P = 0.009) and were slightly lower during the night than day (95 vs. 99 mg/dl, P < 0.001).
CONCLUSIONS - Glucose values <= 60 and >140 mg/dl, measured with CGM, are uncommon in healthy, nondiabetic individuals. CGM may be useful to evaluate glucose tolerance in nondiabetic individuals over time. Furthermore, these data provide a basis for comparison for studies that use CGM to assess glucose control in subjects with diabetes.
Details
- Title: Subtitle
- Variation of Interstitial Glucose Measurements Assessed by Continuous Glucose Monitors in Healthy, Nondiabetic Individuals
- Creators
- Larry A. FoxRoy W. BeckDongyuan XingH. Peter ChaseLisa K. GilliamIrl HirschCraig KollmanLori LaffelJoyce LeeKatrina J. RuedyWilliam V. TamborlaneMichael TanseyDarrell M. WilsonJuvenile Diabetes Research Foundation Continuous Glucose Monitoring Study Group
- Resource Type
- Journal article
- Publication Details
- Diabetes care, Vol.33(6), pp.1297-1299
- DOI
- 10.2337/dc09-1971
- PMID
- 20215454
- PMCID
- PMC2875442
- NLM abbreviation
- Diabetes Care
- ISSN
- 0149-5992
- eISSN
- 1935-5548
- Publisher
- Amer Diabetes Assoc
- Number of pages
- 3
- Grant note
- K08 DK082386 / NIDDK NIH HHS; United States Department of Health & Human Services; National Institutes of Health (NIH) - USA; NIH National Institute of Diabetes & Digestive & Kidney Diseases (NIDDK) K08DK082386 / NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES; United States Department of Health & Human Services; National Institutes of Health (NIH) - USA; NIH National Institute of Diabetes & Digestive & Kidney Diseases (NIDDK)
- Language
- English
- Date published
- 06/01/2010
- Academic Unit
- Endocrinology and Diabetes; Stead Family Department of Pediatrics; Fraternal Order of Eagles Diabetes Research Center
- Record Identifier
- 9984353849702771
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