Journal article
Variations in PET/CT methodology for oncologic imaging at U.S. academic medical centers: an imaging response assessment team survey
The Journal of nuclear medicine (1978), Vol.52(2), pp.311-317
02/2011
DOI: 10.2967/jnumed.109.074104
PMCID: PMC3889016
PMID: 21233185
Abstract
In 2005, 8 Imaging Response Assessment Teams (IRATs) were funded by the National Cancer Institute (NCI) as supplemental grants to existing NCI Cancer Centers. After discussion among the IRATs regarding the need for increased standardization of clinical and research PET/CT methodology, it became apparent that data acquisition and processing approaches differ considerably among centers. To determine the variability in detail, a survey of IRAT sites and IRAT affiliates was performed.
A 34-question instrument evaluating patient preparation, scanner type, performance approach, display, and analysis was developed. Fifteen institutions, including the 8 original IRATs and 7 institutions that had developed affiliate IRATs, were surveyed.
The major areas of variation were (18)F-FDG dose (259-740 MBq [7-20 mCi]) uptake time (45-90 min), sedation (never to frequently), handling of diabetic patients, imaging time (2-7 min/bed position), performance of diagnostic CT scans as a part of PET/CT, type of acquisition (2-dimensional vs. 3-dimensional), CT technique, duration of fasting (4 or 6 h), and (varying widely) acquisition, processing, display, and PACS software--with 4 sites stating that poor-quality images appear on PACS.
There is considerable variability in the way PET/CT scans are performed at academic institutions that are part of the IRAT network. This variability likely makes it difficult to quantitatively compare studies performed at different centers. These data suggest that additional standardization in methodology will be required so that PET/CT studies, especially those performed quantitatively, are more comparable across sites.
Details
- Title: Subtitle
- Variations in PET/CT methodology for oncologic imaging at U.S. academic medical centers: an imaging response assessment team survey
- Creators
- Michael M Graham - Department of Radiology, University of Iowa, Iowa City, IA 52242, USA. michael-graham@uiowa.eduRamsey D BadawiRichard L Wahl
- Resource Type
- Journal article
- Publication Details
- The Journal of nuclear medicine (1978), Vol.52(2), pp.311-317
- Publisher
- United States
- DOI
- 10.2967/jnumed.109.074104
- PMID
- 21233185
- PMCID
- PMC3889016
- ISSN
- 0161-5505
- eISSN
- 1535-5667
- Grant note
- P30 CA016058 / NCI NIH HHS P30 CA006973 / NCI NIH HHS 3P30CA047904 / NCI NIH HHS 5P30CA091842 / NCI NIH HHS P30 CA023074 / NCI NIH HHS P30 CA008748 / NCI NIH HHS P30 CA086862 / NCI NIH HHS 3P30CA093373 / NCI NIH HHS P30 CA093373 / NCI NIH HHS P30 CA091842 / NCI NIH HHS 3P30CA016058 / NCI NIH HHS 2P30CA023074 / NCI NIH HHS 3P30CA006973 / NCI NIH HHS P30 CA047904 / NCI NIH HHS 3P30CA008748 / NCI NIH HHS 5P30CA086862 / NCI NIH HHS
- Language
- English
- Date published
- 02/2011
- Academic Unit
- Radiology; Radiation Oncology
- Record Identifier
- 9984046932502771
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