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Variations in liver allocation systems across continents with a focus on MELD exceptions
Journal article   Peer reviewed

Variations in liver allocation systems across continents with a focus on MELD exceptions

Tomohiro Tanaka, Abdul Rahman Hakeem, Ryan Chadha, Wojciech Polak, Claire Francoz, Carmen Vinaixa, Francesco Paolo Russo, Gökhan Kabacam, Pål Dag Line, Ken Liu, …
Liver transplantation, Vol.32(5), pp.748-764
05/2026
DOI: 10.1097/LVT.0000000000000751
PMID: 41100744

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Abstract

Variations in liver allocation systems world-wide are presented, with a specific focus on regional differences and their potential impact on outcomes, with the goal to serve as a reference for future policy development. Summaries of liver allocation across multiple European, Scandinavian, Asian systems as well as the combined allocation system of Australia plus Canada, the United States, and the systems in Central America, South American, and the Caribbean are reviewed. A comprehensive comparison of how different regions address MELD exceptions, primarily focusing on hepatocellular carcinoma, along with the most common etiologies of liver disease requiring transplantation. Additionally, the adoption of living donation and donation after circulatory death (DCD) is discussed. The study involves contributions from a diverse group of world experts in liver transplantation and may serve as an essential resource to foster international dialogue as countries strive to optimize organ allocation policy, including MELD exceptions.
International Liver Transplantation Society allocation policy hepatocellular carcinoma

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