Journal article
Variations in seasonal solar insolation are associated with a history of suicide attempts in bipolar I disorder
International Journal of Bipolar Disorders, Vol.9(1), pp.1-14
09/01/2021
DOI: 10.1186/s40345-021-00231-7
PMCID: PMC8408297
PMID: 34467430
Abstract
Abstract Background Bipolar disorder is associated with circadian disruption and a high risk of suicidal behavior. In a previous exploratory study of patients with bipolar I disorder, we found that a history of suicide attempts was associated with differences between winter and summer levels of solar insolation. The purpose of this study was to confirm this finding using international data from 42% more collection sites and 25% more countries. Methods Data analyzed were from 71 prior and new collection sites in 40 countries at a wide range of latitudes. The analysis included 4876 patients with bipolar I disorder, 45% more data than previously analyzed. Of the patients, 1496 (30.7%) had a history of suicide attempt. Solar insolation data, the amount of the sun’s electromagnetic energy striking the surface of the earth, was obtained for each onset location (479 locations in 64 countries). Results This analysis confirmed the results of the exploratory study with the same best model and slightly better statistical significance. There was a significant inverse association between a history of suicide attempts and the ratio of mean winter insolation to mean summer insolation (mean winter insolation/mean summer insolation). This ratio is largest near the equator which has little change in solar insolation over the year, and smallest near the poles where the winter insolation is very small compared to the summer insolation. Other variables in the model associated with an increased risk of suicide attempts were a history of alcohol or substance abuse, female gender, and younger birth cohort. The winter/summer insolation ratio was also replaced with the ratio of minimum mean monthly insolation to the maximum mean monthly insolation to accommodate insolation patterns in the tropics, and nearly identical results were found. All estimated coefficients were significant at p < 0.01. Conclusion A large change in solar insolation, both between winter and summer and between the minimum and maximum monthly values, may increase the risk of suicide attempts in bipolar I disorder. With frequent circadian rhythm dysfunction and suicidal behavior in bipolar disorder, greater understanding of the optimal roles of daylight and electric lighting in circadian entrainment is needed.
Details
- Title: Subtitle
- Variations in seasonal solar insolation are associated with a history of suicide attempts in bipolar I disorder
- Creators
- Michael Bauer - Department of Psychiatry and Psychotherapy, Faculty of Medicine, University Hospital Carl Gustav Carus, Technische Universität DresdenTasha Glenn - ChronoRecord AssociationEric D. Achtyes - Division of Psychiatry and Behavioral Medicine, Michigan State University College of Human MedicineMartin Alda - Department of Psychiatry, Dalhousie UniversityEsen Agaoglu - Department of Psychiatry, Hacettepe University Faculty of MedicineKürşat Altınbaş - Department of Psychiatry, Selcuk University Faculty of Medicine, Mazhar Osman Mood CenterOle A. Andreassen - NORMENT Centre, Division of Mental Health and Addiction, Oslo University Hospital and Institute of Clinical Medicine, University of OsloElias Angelopoulos - Department of Psychiatry, National and Capodistrian University of Athens, Medical School, Eginition HospitalRaffaella Ardau - Section of Neurosciences and Clinical Pharmacology, Department of Biomedical Sciences, University of CagliariEdgar Arrua Vares - Department of Psychiatry and Psychotherapy, Faculty of Medicine, University Hospital Carl Gustav Carus, Technische Universität DresdenMemduha Aydin - Department of Psychiatry, Selcuk University Faculty of MedicineYavuz Ayhan - Department of Psychiatry, Hacettepe University Faculty of MedicineChristopher Baethge - Department of Psychiatry and Psychotherapy, University of Cologne Medical SchoolRita Bauer - Department of Psychiatry and Psychotherapy, Faculty of Medicine, University Hospital Carl Gustav Carus, Technische Universität DresdenBernhard T. Baune - Department of Psychiatry, University of MünsterCeylan Balaban - Department of Psychiatry, Psychosomatic Medicine and Psychotherapy, University Hospital Frankfurt, Johann Wolfgang Goethe-Universität Frankfurt am MainClaudia Becerra-Palars - National Institute of Psychiatry “Ramón de la Fuente Muñiz”Aniruddh P. Behere - Child and Adolescent Psychiatry, Helen DeVos Children’s Hospital, Michigan State University-CHMPrakash B. Behere - Department of Psychiatry, Jawaharlal Nehru Medical College, Datta Meghe Institute of Medical Sciences (Deemed University)Habte Belete - Department of Psychiatry, College of Medicine and Health Sciences, Bahir Dar UniversityTilahun Belete - Department of Psychiatry, College of Medicine and Health Sciences, Bahir Dar UniversityGabriel Okawa Belizario - Bipolar Disorder Research Program, Department of Psychiatry, University of São Paulo Medical SchoolFrank Bellivier - Département de Psychiatrie et de Médecine Addictologique, Assistance Publique-Hôpitaux de Paris, INSERM UMR-S1144, Université de Paris, FondaMental FoundationRobert H. Belmaker - Professor Emeritus of Psychiatry, Ben Gurion University of the NegevFrancesco Benedetti - University Vita-Salute San RaffaeleMichael Berk - Deakin University, IMPACT-The Institute for Mental and Physical Health and Clinical Translation, School of Medicine, Barwon HealthYuly Bersudsky - Department of Psychiatry, Faculty of Health Sciences, Beer Sheva Mental Health Center, Ben Gurion University of the NegevŞule Bicakci - Department of Psychiatry, Hacettepe University Faculty of MedicineHarriet Birabwa-Oketcho - Butabika HospitalThomas D. Bjella - NORMENT Centre, Division of Mental Health and Addiction, Oslo University Hospital and Institute of Clinical Medicine, University of OsloConan Brady - Department of Psychiatry, Trinity College Dublin, St Patrick’s University HospitalJorge Cabrera - Mood Disorders Clinic, Dr. Jose Horwitz Psychiatric InstituteMarco Cappucciati - Department of Mental Health and Substance AbuseAngela Marianne Paredes Castro - Deakin University, IMPACT-The Institute for Mental and Physical Health and Clinical Translation, School of Medicine, Barwon HealthWei-Ling Chen - Department of Psychiatry, Chiayi Branch, Taichung Veterans General HospitalEric Y. Wo Cheung - Private PracticeSilvia Chiesa - Department of Mental Health and Substance AbuseMarie Crowe - Department of Psychological Medicine, University of OtagoAlessandro Cuomo - Department of Molecular Medicine, University of Siena School of MedicineSara Dallaspezia - Psychiatry and Clinical Psychobiology, Division of Neuroscience, San Raffaele Scientific InstituteMaria Del Zompo - Section of Neurosciences and Clinical Pharmacology, Department of Biomedical Sciences, University of CagliariPratikkumar Desai - Pine Rest Christian Mental Health ServicesSeetal Dodd - Deakin University, IMPACT-The Institute for Mental and Physical Health and Clinical Translation, School of Medicine, Barwon HealthMarkus Donix - Department of Psychiatry and Psychotherapy, Faculty of Medicine, University Hospital Carl Gustav Carus, Technische Universität DresdenBruno Etain - Département de Psychiatrie et de Médecine Addictologique, Assistance Publique-Hôpitaux de Paris, INSERM UMR-S1144, Université de Paris, FondaMental FoundationAndrea Fagiolini - Department of Molecular Medicine, University of Siena School of MedicineFrederike T. Fellendorf - Department of Psychiatry and Psychotherapeutic Medicine, Medical University GrazEwa Ferensztajn-Rochowiak - Department of Adult Psychiatry, Poznan University of Medical SciencesJess G. Fiedorowicz - Department of Psychiatry, School of Epidemiology and Public Health, University of OttawaKostas N. Fountoulakis - 3rd Department of Psychiatry, School of Medicine, Faculty of Health Sciences, Aristotle University of ThessalonikiMark A. Frye - Department of Psychiatry and Psychology, Mayo Clinic Depression Center, Mayo ClinicPierre A. Geoffroy - Département de Psychiatrie et d’addictologie, AP-HP, Hopital Bichat-Claude BernardAna Gonzalez-Pinto - BIOARABA, Department of Psychiatry, University Hospital of Alava, University of the Basque Country, CIBERSAMJohn F. Gottlieb - Department of Psychiatry, Feinberg School of Medicine, Northwestern UniversityPaul Grof - Mood Disorders Center of Ottawa and the Department of Psychiatry, University of TorontoBartholomeus C. M. Haarman - Department of Psychiatry, University Medical Center Groningen, University of GroningenHirohiko Harima - Department of Psychiatry, Tokyo Metropolitan Matsuzawa HospitalMathias Hasse-Sousa - Department of Psychiatry, Universidade Federal do Rio Grande do SulChantal Henry - Department of Psychiatry, GHU Paris Psychiatrie & NeurosciencesLone Høffding - Department of Clinical Research, University of Southern DenmarkJosselin Houenou - Université Paris Est Créteil, INSERM, IMRB, Translational Neuropsychiatry, Fondation FondaMentalMassimiliano Imbesi - Department of Mental Health and Substance AbuseErkki T. Isometsä - Department of Psychiatry, University of Helsinki and Helsinki University HospitalMaja Ivkovic - University Clinical Center of Serbia, Clinic for PsychiatrySven Janno - Department of Psychiatry, University of TartuSimon Johnsen - Unit for Psychiatric Research, Aalborg University HospitalFlávio Kapczinski - Department of Psychiatry, Universidade Federal do Rio Grande do SulGregory N. Karakatsoulis - 3rd Department of Psychiatry, School of Medicine, Faculty of Health Sciences, Aristotle University of ThessalonikiMathias Kardell - Department of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology, The Sahlgrenska Academy, University of GothenburgLars Vedel Kessing - Copenhagen Affective Disorder Research Center (CADIC), Psychiatric Center Copenhagen, RigshospitaletSeong Jae Kim - Department of Psychiatry, Cheongju HospitalBarbara König - BIPOLAR Zentrum Wiener NeustadtTimur L. Kot - Khanty-Mansiysk Clinical Psychoneurological HospitalMichael Koval - Department of Neuroscience, Michigan State UniversityMauricio Kunz - Department of Psychiatry, Universidade Federal do Rio Grande do SulBeny Lafer - Bipolar Disorder Research Program, Department of Psychiatry, University of São Paulo Medical SchoolMikael Landén - Department of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology, The Sahlgrenska Academy, University of GothenburgErik R. Larsen - Mental Health Department Odense, University Clinic and Department of Regional Health Research, University of Southern DenmarkMelanie Lenger - Department of Psychiatry and Psychotherapeutic Medicine, Medical University GrazUte Lewitzka - Department of Psychiatry and Psychotherapy, Faculty of Medicine, University Hospital Carl Gustav Carus, Technische Universität DresdenRasmus W. Licht - Psychiatry, Aalborg University HospitalCarlos Lopez-Jaramillo - Mood Disorders Program, Hospital Universitario San Vicente Fundación, Research Group in Psychiatry, Department of Psychiatry, Faculty of Medicine, Universidad de AntioquiaAlan MacKenzie - Forensic Psychiatry, University of Glasgow, NHS Greater Glasgow and ClydeHelle Østergaard Madsen - Copenhagen University Hospitals, Psychiatric Centre CopenhagenSimone Alberte Kongstad A. Madsen - Unit for Psychiatric Research, Aalborg University HospitalJayant Mahadevan - Department of Psychiatry, National Institute of Mental Health and Neuro Sciences (NIMHANS)Agustine Mahardika - Department of Psychiatry, Faculty of Medicine, Mataram UniversityMirko Manchia - Department of Pharmacology, Dalhousie UniversityWendy Marsh - Department of Psychiatry, University of Massachusetts Medical SchoolMonica Martinez-Cengotitabengoa - Osakidetza, Basque Health Service, BioAraba Research Institute, University of the Basque CountryKlaus Martiny - Copenhagen University Hospitals, Psychiatric Centre CopenhagenYuki Mashima - Department of Neuropsychiatry, Keio University School of MedicineDeclan M. McLoughlin - Department of Psychiatry, Trinity College Institute of Neuroscience, Trinity College Dublin, St Patrick’s University HospitalYbe Meesters - Department of Psychiatry, University Medical Center Groningen, University of GroningenIngrid Melle - NORMENT Centre, Division of Mental Health and Addiction, Oslo University Hospital and Institute of Clinical Medicine, University of OsloFátima Meza-Urzúa - National Institute of Psychiatry “Ramón de la Fuente Muñiz”Mok Yee Ming - Department of General Psychiatry, Mood Disorders Unit, Institute of Mental HealthScott Monteith - Michigan State University College of Human MedicineMuthukumaran Moorthy - Department of Psychiatry, National Institute of Mental Health and Neuro Sciences (NIMHANS)Gunnar Morken - Department of Mental Health, Norwegian University of Science and Technology-NTNUEnrica Mosca - Section of Neurosciences and Clinical Pharmacology, Department of Biomedical Sciences, University of CagliariAnton A. Mozzhegorov - Soviet Psychoneurological HospitalRodrigo Munoz - Department of Psychiatry, University of California San DiegoStarlin V. Mythri - Asha Bipolar Clinic, Asha HospitalFethi Nacef - Razi Hospital, Faculty of Medicine, University of Tunis-El ManarRavi K. Nadella - Department of Psychiatry, National Institute of Mental Health and Neuro Sciences (NIMHANS)Takako Nakanotani - Affective Disorders Research Project, Tokyo Metropolitan Institute of Medical ScienceRené Ernst Nielsen - Psychiatry, Aalborg University HospitalClaire O‘Donovan - Department of Psychiatry, Dalhousie UniversityAdel Omrani - Tunisian Bipolar ForumYamima Osher - Department of Psychiatry, Faculty of Health Sciences, Beer Sheva Mental Health Center, Ben Gurion University of the NegevUta Ouali - Razi Hospital, Faculty of Medicine, University of Tunis-El ManarMaja Pantovic-Stefanovic - University Clinical Center of Serbia, Clinic for PsychiatryPornjira Pariwatcharakul - Department of Psychiatry, Faculty of Medicine, Siriraj Hospital, Mahidol UniversityJoanne Petite - Department of Psychiatry, Dalhousie UniversityAndrea Pfennig - Department of Psychiatry and Psychotherapy, Faculty of Medicine, University Hospital Carl Gustav Carus, Technische Universität DresdenYolanda Pica Ruiz - Hospital “Ángeles del Pedregal”Maximilian Pilhatsch - Department of Psychiatry and Psychotherapy, Faculty of Medicine, University Hospital Carl Gustav Carus, Technische Universität DresdenMarco Pinna - Section of Psychiatry, Department of Medical Science and Public Health, University of CagliariMaurizio Pompili - Department of Neurosciences, Mental Health and Sensory Organs, Sant’Andrea Hospital, Sapienza University of RomeRichard Porter - Department of Psychological Medicine, University of OtagoDanilo Quiroz - Deparment of Psychiatry, Diego Portales UniversityFrancisco Diego Rabelo-da-Ponte - Department of Psychiatry, Universidade Federal do Rio Grande do SulRaj Ramesar - SA MRC Genomic and Precision Medicine Research Unit, Division of Human Genetics, Department of Pathology, Institute of Infectious Diseases and Molecular Medicine, University of Cape TownNatalie Rasgon - Department of Psychiatry and Behavioral Sciences, Stanford School of MedicineWoraphat Ratta-apha - Department of Psychiatry, Faculty of Medicine, Siriraj Hospital, Mahidol UniversityMichaela Ratzenhofer - Department of Psychiatry and Psychotherapeutic Medicine, Medical University GrazMaria Redahan - Department of Psychiatry, Trinity College Dublin, St Patrick’s University HospitalM. S. Reddy - Asha Bipolar Clinic, Asha HospitalAndreas Reif - Department of Psychiatry, Psychosomatic Medicine and Psychotherapy, University Hospital Frankfurt, Johann Wolfgang Goethe-Universität Frankfurt am MainEva Z. Reininghaus - Department of Psychiatry and Psychotherapeutic Medicine, Medical University GrazJenny Gringer Richards - Departments of Psychiatry, Epidemiology, and Internal Medicine, Iowa Neuroscience Institute, The University of IowaPhilipp Ritter - Department of Psychiatry and Psychotherapy, Faculty of Medicine, University Hospital Carl Gustav Carus, Technische Universität DresdenJanusz K. Rybakowski - Department of Adult Psychiatry, Poznan University of Medical SciencesLeela Sathyaputri - Departments of Psychiatry, Epidemiology, and Internal Medicine, Iowa Neuroscience Institute, The University of IowaÂngela M. Scippa - Department of Neuroscience and Mental Health, Federal University of BahiaChristian Simhandl - Bipolar Zentrum Wiener Neustadt, Sigmund Freud Privat UniversitätEmanuel Severus - Department of Psychiatry and Psychotherapy, Faculty of Medicine, University Hospital Carl Gustav Carus, Technische Universität DresdenDaniel Smith - Centre for Clinical Brain Sciences, University of EdinburghJosé Smith - Bipolar Disorder Program, Neuroscience Institute, Favaloro UniversityPaul W. Stackhouse - Science Directorate/Climate Science Branch, NASA Langley Research CenterDan J. Stein - Department of Psychiatry, MRC Unit On Risk and Resilience in Mental Disorders, University of Cape TownKellen Stilwell - Pine Rest Christian Mental Health ServicesSergio Strejilevich - Bipolar Disorder Program, Neuroscience Institute, Favaloro UniversityKuan-Pin Su - College of Medicine, China Medical University (CMU)Mythily Subramaniam - Research Division, Institute of Mental HealthAhmad Hatim Sulaiman - Department of Psychological Medicine, Faculty of Medicine, University of MalayaKirsi Suominen - Department of Social Services and Health Care, Psychiatry, City of HelsinkiAndi J. Tanra - Department of Psychiatry, Faculty of Medicine, Hasanuddin UniversityYoshitaka Tatebayashi - Affective Disorders Research Project, Tokyo Metropolitan Institute of Medical ScienceWen Lin Teh - Research Division, Institute of Mental HealthLeonardo Tondo - McLean Hospital-Harvard Medical SchoolCarla Torrent - Clinical Institute of Neuroscience, Hospital Clinic, University of Barcelona, IDIBAPS, CIBERSAMDaniel Tuinstra - Pine Rest Christian Mental Health ServicesTakahito Uchida - Department of Neuropsychiatry, Keio University School of MedicineArne E. Vaaler - Department of Mental Health, Norwegian University of Science and Technology-NTNUJulia Veeh - Department of Psychiatry, Psychosomatic Medicine and Psychotherapy, University Hospital Frankfurt, Johann Wolfgang Goethe-Universität Frankfurt am MainEduard Vieta - Clinical Institute of Neuroscience, Hospital Clinic, University of Barcelona, IDIBAPS, CIBERSAMBiju Viswanath - Department of Psychiatry, National Institute of Mental Health and Neuro Sciences (NIMHANS)Maria Yoldi-Negrete - Subdirección de Investigaciones Clínicas, Instituto Nacional de Psiquiatría Ramón de la Fuente MuñízOguz Kaan Yalcinkaya - Department of Psychiatry, Hacettepe University Faculty of MedicineAllan H. Young - Department of Psychological Medicine, Institute of Psychiatry, Psychology and Neuroscience, King’s College LondonYosra Zgueb - Razi Hospital, Faculty of Medicine, University of Tunis-El ManarPeter C. Whybrow - Department of Psychiatry and Biobehavioral Sciences, Semel Institute for Neuroscience and Human Behavior, University of California Los Angeles (UCLA)
- Resource Type
- Journal article
- Publication Details
- International Journal of Bipolar Disorders, Vol.9(1), pp.1-14
- DOI
- 10.1186/s40345-021-00231-7
- PMID
- 34467430
- PMCID
- PMC8408297
- NLM abbreviation
- Int J Bipolar Disord
- ISSN
- 2194-7511
- eISSN
- 2194-7511
- Publisher
- SpringerOpen
- Grant note
- DOI: 10.13039/501100000925, name: National Health and Medical Research Council, award: 1156072; DOI: 10.13039/501100001665, name: Agence Nationale de la Recherche, award: ANR-11-IDEX-0004, ANR-10-COHO-10–01, ANR-14-CE35–0035; DOI: 10.13039/501100001349, name: National Medical Research Council, award: NMRC/CG/M002/2017_IMH, NMRC/CG/M002/2017_IMH, NMRC/CG/M002/2017_IMH; DOI: 10.13039/501100002957, name: Technische Universität Dresden
- Language
- English
- Date published
- 09/01/2021
- Academic Unit
- Radiology; Psychiatry; Epidemiology; Iowa Neuroscience Institute; Surgery
- Record Identifier
- 9984129908202771
Metrics
18 Record Views