Journal article
Vasoconstrictor response to simulated diving in man
Journal of applied physiology (1948), Vol.25(5), pp.542-549
11/1968
DOI: 10.1152/jappl.1968.25.5.542
PMID: 5687360
Abstract
A vasoconstrictor response to simulated diving has not been demonstrated clearly in man. Intra-arterial blood pressure and blood flow to the forearm and finger were measured simultaneously. Measurements of blood flow were obtained with plethysmographs, and observations were made during breath holding and during immersion of the face in water. Both breath holding and immersion caused vasoconstriction as indicated by a reduction in blood flow and an increase in arterial pressure. The reduction in blood flow to the finger was greater than the reduction in flow to the forearm, and the vasoconstrictor response was more pronounced with immersion than with breath holding. A bradycardia was observed during immersion and breath holding, and the intravenous administration of atropine antagonized this bradycardia without altering the vasoconstrictor responses. The possibility that a reflex cholinergic vasodilation might have reduced the net vasoconstrictor responses in the forearm was thus excluded. A significant systolic pressure gradient occurred between the brachial and digital arteries during immersion, indicating constriction of arteries upstream from the digital arteries. The volumes of the congested finger and forearm decreased during breath holding and immersion of the face when the pressure in the congesting cuffs was constant, suggesting decreased compliance of capacity vessels.
Details
- Title: Subtitle
- Vasoconstrictor response to simulated diving in man
- Creators
- Donald D HeistadFrancois M AbboundJohn W Eckstein
- Resource Type
- Journal article
- Publication Details
- Journal of applied physiology (1948), Vol.25(5), pp.542-549
- Publisher
- United States
- DOI
- 10.1152/jappl.1968.25.5.542
- PMID
- 5687360
- ISSN
- 0021-8987
- eISSN
- 2691-2473
- Language
- English
- Date published
- 11/1968
- Academic Unit
- Cardiovascular Medicine; Fraternal Order of Eagles Diabetes Research Center; Neuroscience and Pharmacology; Internal Medicine
- Record Identifier
- 9984040564802771
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