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Venous Thromboembolism Risk Assessment in Hospitalized Cancer Patients: A Single Center Study
Journal article   Open access   Peer reviewed

Venous Thromboembolism Risk Assessment in Hospitalized Cancer Patients: A Single Center Study

Supratik Rayamajhi, Shiva Shrotriya, Manoj Rai, Prajwal Dhakal, Nishraj Basnet, Mukta Sharma, Alexa Lupi and Joseph Gardiner
Clinical and applied thrombosis/hemostasis, Vol.29, pp.1-7
11/01/2023
DOI: 10.1177/10760296231206808
PMCID: PMC10621296
PMID: 37908071
url
https://doi.org/10.1177/10760296231206808View
Published (Version of record) Open Access

Abstract

This study aimed to identify predictors of venous thromboembolism (VTE) in hospitalized cancer patients and develop a predictive model using demographic, clinical, and laboratory data. Our analysis showed that patient groups categorized under a very high risk, and high risk, patients with low hemoglobin levels and renal disease were at a significantly increased risk of developing VTE. We developed a VTE risk-assessment model (RAM) with moderate discriminatory performance, high specificity, and negative predictive value, indicating its potential utility in identifying patients without VTE risk. However, the model's positive predictive value and sensitivity were low due to the low prevalence of VTE within the analyzed population. Future studies are needed to analyze additional predictive factors, and to validate the effectiveness of our VTE RAM to safely rule out VTE, compare it with other VTE RAMs in hospitalized cancer patients, and address any limitations of our study.
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