Journal article
Vertebral Augmentation for Compression Fractures Caused by Malignant Disease
Journal of the National Comprehensive Cancer Network, Vol.8(9), pp.1095-1102
09/2010
DOI: 10.6004/jnccn.2010.0078
PMID: 20876546
Abstract
Vertebral compression fractures are common in malignant disease and frequently cause severe back pain. However, management of that pain with conventional medical, radiotherapy, or surgical modalities is often inadequate. Vertebral augmentation techniques, such as vertebroplasty and kyphoplasty, are minimally invasive techniques in which methylmethacrylate bone cement is percutaneously injected into compressed vertebral bodies. Vertebral augmentation often improves mechanical stability of compressed vertebrae, provides pain relief, and may prevent progression of vertebral collapse. Kyphoplasty may provide increased chance for vertebral body height restoration, but the clinical importance of slight change in vertebral body height is unclear. Vertebral augmentation can be used in conjunction with other treatment modalities, and associated pain relief may improve patient tolerance of needed antitumor therapies, such as radiation therapy. Vertebral augmentation is generally very well tolerated, and complications associated with bone cement extravasation beyond the vertebral body have rarely been reported. Because it often provides good to excellent relief of otherwise intractable pain and is generally well tolerated, vertebral augmentation is becoming a first-line agent for management of painful vertebral compression fractures, especially in the setting of malignant disease.
Details
- Title: Subtitle
- Vertebral Augmentation for Compression Fractures Caused by Malignant Disease
- Creators
- Rahul Rastogi - From the Department of Anesthesiology, Washington University School of Medicine, St. Louis, MissouriTrusharth Patel - From the Department of Anesthesiology, Washington University School of Medicine, St. Louis, MissouriRobert A Swarm - From the Department of Anesthesiology, Washington University School of Medicine, St. Louis, Missouri
- Resource Type
- Journal article
- Publication Details
- Journal of the National Comprehensive Cancer Network, Vol.8(9), pp.1095-1102
- DOI
- 10.6004/jnccn.2010.0078
- PMID
- 20876546
- ISSN
- 1540-1405
- eISSN
- 1540-1413
- Language
- English
- Date published
- 09/2010
- Academic Unit
- Anesthesia
- Record Identifier
- 9984007183802771
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