Journal article
Vertebral compression fractures: distinction between benign and malignant causes with MR imaging
Radiology, Vol.172(1), pp.215-218
1989
DOI: 10.1148/radiology.172.1.2740506
PMID: 2740506
Abstract
Magnetic resonance (MR) imaging was performed on 64 patients with 109 vertebral compression fractures, the cause of which could not be determined from plain radiographs. Twenty-five fractures were due to malignancy; 84 were caused by a benign process. In 22 of the 25 fractures caused by malignancy, MR images showed complete replacement of normal bone marrow, whereas 47 of the 61 benign fractures without history of trauma had complete preservation of normal bone marrow. The remaining 14 benign fractures had incompletely preserved bone marrow in a regular pattern. In two of the three remaining malignant fractures, the bone marrow replacement also was incomplete but with an irregular pattern. In cases of recent trauma or primary bone marrow abnormalities, the configuration and signal of remaining bone marrow were not useful in differentiating among malignancy, osteoporosis, and other benign processes. When criteria based on complete loss or preservation of marrow and marrow configuration in cases of incomplete loss were used, the accuracy in differentiating benign from malignant fractures was 94%. MR imaging may be a useful adjunct in differentiating benign from metastatic fractures and may provide information not available with other imaging methods.
Details
- Title: Subtitle
- Vertebral compression fractures: distinction between benign and malignant causes with MR imaging
- Creators
- William T C Yuh - Univ. Iowa hosp., dep. radiology, Iowa City IA 52242, United StatesCharles K Zachar - Univ. Iowa hosp., dep. radiology, Iowa City IA 52242, United StatesThomas J Barloon - Univ. Iowa hosp., dep. radiology, Iowa City IA 52242, United StatesYutaka Sato - Univ. Iowa hosp., dep. radiology, Iowa City IA 52242, United StatesWilliam J Sickels - Univ. Iowa hosp., dep. radiology, Iowa City IA 52242, United StatesDonald R Hawes - Univ. Iowa hosp., dep. radiology, Iowa City IA 52242, United States
- Resource Type
- Journal article
- Publication Details
- Radiology, Vol.172(1), pp.215-218
- Publisher
- Radiological Society of North America; Oak Brook, IL
- DOI
- 10.1148/radiology.172.1.2740506
- PMID
- 2740506
- ISSN
- 0033-8419
- eISSN
- 1527-1315
- Language
- English
- Date published
- 1989
- Academic Unit
- Radiology; Stead Family Department of Pediatrics
- Record Identifier
- 9984051536102771
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