Viral Coinfection is Associated with Improved Outcomes in Emergency Department Patients with SARS-CoV-2

Elizabeth M. Goldberg; Kohei Hasegawa; Alexis Lawrence; Jeffrey A. Kline; Carlos A Camargo Jr; RECOVER investigators

doi:10.5811/westjem.2021.8.53590

Back

Viral Coinfection is Associated with Improved Outcomes in Emergency Department Patients with SARS-CoV-2

Journal article

Open access

Peer reviewed

Viral Coinfection is Associated with Improved Outcomes in Emergency Department Patients with SARS-CoV-2

Elizabeth M. Goldberg, Kohei Hasegawa, Alexis Lawrence, Jeffrey A. Kline, Carlos A Camargo Jr and RECOVER investigators

The western journal of emergency medicine, Vol.22(6), pp.1262-1269

11/01/2021

DOI: 10.5811/westjem.2021.8.53590

PMCID: PMC8597701

PMID: 34787549

Files and links (1)

url

https://doi.org/10.5811/westjem.2021.8.53590View

Published (Version of record) Open Access

Abstract

Introduction: Coinfection with severe acute respiratory syndrome-coronavirus 2 SARS-CoV-2) and another virus may influence the clinical trajectory of emergency department (ED) patients. However, little empirical data exists on the clinical outcomes of coinfection with SARS-CoV-2 Methods: In this retrospective cohort analysis, we included adults presenting to the ED with confirmed, symptomatic coronavirus 2019 who also underwent testing for additional viral pathogens within 24 hours. To investigate the association between coinfection status with each of the outcomes. we performed logistic regression. Results: Of 6,913 ED patients, 5.7% had coinfection. Coinfected individuals were less likely to experience index visit or 30-day hospitalization (odds ratio [ORS 0.57; 95% confidence interval [CI], 0.36-0.90 and OR 0.39; 95% CI, 0.25-0.62, respectively). Conclusion: Coinfection is relatively uncommon in symptomatic ED patients with SARS-CoV-2 and the clinical short- and long-term outcomes are more favorable in coinfected individuals.

Emergency Medicine

Life Sciences & Biomedicine

Science & Technology

Details

Title: Subtitle: Viral Coinfection is Associated with Improved Outcomes in Emergency Department Patients with SARS-CoV-2
Creators: Elizabeth M. Goldberg - Brown University
Kohei Hasegawa - Massachusetts General Hospital
Alexis Lawrence - Brown University
Jeffrey A. Kline - Wayne State University
Carlos A Camargo Jr - Harvard Medical School
RECOVER investigators
Contributors: Marina Del Rios (Contributor) - University of Iowa, Emergency Medicine
Hans House (Contributor) - University of Iowa, Emergency Medicine
Resource Type: Journal article
Publication Details: The western journal of emergency medicine, Vol.22(6), pp.1262-1269
DOI: 10.5811/westjem.2021.8.53590
PMID: 34787549
PMCID: PMC8597701
NLM abbreviation: West J Emerg Med
ISSN: 1936-900X
eISSN: 1936-9018
Publisher: Westjem
Number of pages: 8
Language: English
Date published: 11/01/2021
Academic Unit: Emergency Medicine
Record Identifier: 9984297143002771

Metrics

12 Record Views