Journal article
Viral Vector–mediated and Cell-based Therapies for Treatment of Cystic Fibrosis
Molecular therapy, Vol.15(2), pp.229-241
02/2007
DOI: 10.1038/sj.mt.6300002
PMID: 17235299
Abstract
Gene and cell-based therapies are considered to be potentially powerful new approaches for the management of cystic fibrosis (CF) lung disease. Despite tremendous efforts that have been made, especially in studies to understand the obstacles to gene delivery, major challenges to the application of these approaches remain to be solved. This article will review the advancements made and challenges remaining in the development of viral vector–mediated and cell-based approaches to treat patients with CF.
Details
- Title: Subtitle
- Viral Vector–mediated and Cell-based Therapies for Treatment of Cystic Fibrosis
- Creators
- Terence R Flotte - Department of Pediatrics, University of Florida, Gainesville, Florida, USAPhilip Ng - Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, Texas, USADoug E Dylla - Program in Gene Therapy, Department of Pediatrics, Carver College of Medicine, University of Iowa, Iowa City, Iowa, USAPaul B McCray - Program in Gene Therapy, Department of Pediatrics, Carver College of Medicine, University of Iowa, Iowa City, Iowa, USAGuoshun Wang - Department of Medicine, Louisiana State University Health Sciences Center, New Orleans, Louisiana, USAJay K Kolls - Children's Hospital of Pittsburgh, Department of Pediatrics, Pittsburgh, Pennsylvania, USAJim Hu - Lung Biology Research Programme, The Hospital for Sick Children and Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Ontario, Canada
- Resource Type
- Journal article
- Publication Details
- Molecular therapy, Vol.15(2), pp.229-241
- Publisher
- Elsevier Inc
- DOI
- 10.1038/sj.mt.6300002
- PMID
- 17235299
- ISSN
- 1525-0016
- eISSN
- 1525-0024
- Language
- English
- Date published
- 02/2007
- Academic Unit
- Microbiology and Immunology; Pulmonary Medicine; Stead Family Department of Pediatrics; Internal Medicine
- Record Identifier
- 9984093498402771
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