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Virus Infection and Titration of SARS-CoV in Mouse Lung
Journal article   Open access   Peer reviewed

Virus Infection and Titration of SARS-CoV in Mouse Lung

Craig Fett, Jincun Zhao and Stanley Perlman
Bio-protocol, Vol.4(6), e1084
2014
DOI: 10.21769/BioProtoc.1084
PMCID: PMC4932841
PMID: 27390761
url
https://doi.org/10.21769/BioProtoc.1084View
Published (Version of record) Open Access

Abstract

Two critical steps when investigating an animal model of a virus infection are consistently successfully infecting animals and accurately determining viral titers in tissue throughout the course of infection. Here we discuss in detail how to infect mice with SARS-CoV and then quantify the titer of virus in the lung.

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