Visual attention and perception in patients with Huntington's disease: Comparisons with other subcortical and cortical dementias

J. Vincent Filoteo; Dean C Delis; Mary J Roman; Theresa Demadura; Emily Ford; Nelson Butters; David P Salmon; Jane Paulsen; Clifford W Shults; Michael Swenson; Neal Swerdlow

doi:10.1080/01688639508405156

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Visual attention and perception in patients with Huntington's disease: Comparisons with other subcortical and cortical dementias

Journal article

Peer reviewed

Visual attention and perception in patients with Huntington's disease: Comparisons with other subcortical and cortical dementias

J. Vincent Filoteo, Dean C Delis, Mary J Roman, Theresa Demadura, Emily Ford, Nelson Butters, David P Salmon, Jane Paulsen, Clifford W Shults, Michael Swenson, …

Journal of clinical and experimental neuropsychology, Vol.17(5), pp.654-667

10/01/1995

DOI: 10.1080/01688639508405156

PMID: 8557807

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Abstract

Shifts in attention were examined in patients with Huntington's disease (HD) using a divided attention paradigm that involved the presentation of global-local stimuli. The HD patients' pattern of performance was compared to the previously reported results of groups of patients with Alzheimer's disease (AD; Filoteo et al., 1992) or Parkinson's disease (PD; Filoteo et al., 1994). Across consecutive trials of the divided attention task, a visual target could appear at either the same global-local level or at a different level. When the target changed levels across consecutive trials, the AD patients demonstrated an impairment in disengaging attention from the level at which the last target appeared, whereas the PD patients were impaired in maintaining their attention at the previously attended level. In contrast to these patterns of performances, the HD patients did not demonstrate a significant impairment in shifting attention between hierarchical levels. Both the AD and the PD patients' abnormal shifting ability was significantly related to the number of errors they made in identifying target stimuli; however, the pattern of the relationship was qualitatively distinct. These results suggest that different attentional mechanisms may underlie AD and PD patients' visual-perceptual deficits. The HD patients' shifting ability was not related to the number of errors they made in identifying target stimuli, suggesting that a different mechanism may account for the visual-perceptual impairments exhibited by these patients.

Details

Title: Subtitle: Visual attention and perception in patients with Huntington's disease: Comparisons with other subcortical and cortical dementias
Creators: J. Vincent Filoteo - University of Utah
Dean C Delis - University of California
Mary J Roman - University of Texas
Theresa Demadura - San Diego State University
Emily Ford - University of California
Nelson Butters - Department of Veterans Affairs Medical Center
David P Salmon - University of California
Jane Paulsen - University of California
Clifford W Shults - University of California
Michael Swenson - University of California
Neal Swerdlow - University of California
Resource Type: Journal article
Publication Details: Journal of clinical and experimental neuropsychology, Vol.17(5), pp.654-667
DOI: 10.1080/01688639508405156
PMID: 8557807
NLM abbreviation: J Clin Exp Neuropsychol
ISSN: 1380-3395
eISSN: 1744-411X
Publisher: Taylor & Francis Group
Language: English
Date published: 10/01/1995
Academic Unit: Psychiatry; Psychological and Brain Sciences
Record Identifier: 9984083823802771

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