Journal article
Visual function 15 years after optic neuritis: a final follow-up report from the Optic Neuritis Treatment Trial
Ophthalmology (Rochester, Minn.), Vol.115(6), pp.1079-e5
06/2008
DOI: 10.1016/j.ophtha.2007.08.004
PMID: 17976727
Abstract
To assess visual function 15 years after acute unilateral optic neuritis. Longitudinal follow-up of a randomized clinical trial. Two hundred ninety-four patients who were randomized in the Optic Neuritis Treatment Trial between 1988 and 1991 and underwent examination in 2006. A neuro-ophthalmic examination included measurements of visual acuity, contrast sensitivity, and visual field. Quality of life was assessed with the National Eye Institute Visual Function Questionnaire and Neuro-ophthalmic Supplement. Abnormal vision and health-related quality-of-life scores. Seventy-two percent of the eyes affected with optic neuritis at study entry had visual acuity of > or = 20/20 and 66% of patients had > or = 20/20 acuity in both eyes. On average, visual function was slightly worse among patients with multiple sclerosis (MS) than among with those without MS. As expected, quality-of-life scores were lower when acuity was reduced and when neurologic disability from MS was present. Long-term visual outcome is favorable for the majority of patients who experience optic neuritis even when MS is present.
Details
- Title: Subtitle
- Visual function 15 years after optic neuritis: a final follow-up report from the Optic Neuritis Treatment Trial
- Creators
- Optic Neuritis Study Group
- Contributors
- Michael Wall (Contributor) - University of Iowa, Ophthalmology and Visual Sciences
- Resource Type
- Journal article
- Publication Details
- Ophthalmology (Rochester, Minn.), Vol.115(6), pp.1079-e5
- Publisher
- United States
- DOI
- 10.1016/j.ophtha.2007.08.004
- PMID
- 17976727
- ISSN
- 0161-6420
- eISSN
- 1549-4713
- Grant note
- U10 EY09435 / NEI NIH HHS
- Language
- English
- Date published
- 06/2008
- Academic Unit
- Neurology; Ophthalmology and Visual Sciences
- Record Identifier
- 9983979995302771
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