Visual prognosis of multifocal choroiditis, punctate inner choroidopathy, and the diffuse subretinal fibrosis syndrome

Jeremiah Brown Jr; James C Folk; Chittaranjan V Reddy; Alan E Kimura

doi:10.1016/S0161-6420(96)30561-7

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Visual prognosis of multifocal choroiditis, punctate inner choroidopathy, and the diffuse subretinal fibrosis syndrome

Journal article

Peer reviewed

Visual prognosis of multifocal choroiditis, punctate inner choroidopathy, and the diffuse subretinal fibrosis syndrome

Jeremiah Brown Jr, James C Folk, Chittaranjan V Reddy and Alan E Kimura

Ophthalmology (Rochester, Minn.), Vol.103(7), pp.1100-1105

07/1996

DOI: 10.1016/S0161-6420(96)30561-7

PMID: 8684800

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Abstract

To characterize the visual prognosis of patients with multifocal choroiditis and panuveitis (MCP), punctate inner choroidopathy (PIC), and the diffuse subretinal fibrosis (DSF) syndrome. Forty-one patients with MCP, 16 with PIC, and 5 with DSF syndrome were evaluated. The mean follow-up was approximately 39 months for patients with MCP, 51 months for patients with PIC, and 59 months for patients with DSF syndrome. Complete ophthalmic examinations were performed, and photofiles were reviewed. The final average visual acuity for patients with MCP was 20/50. Forty-five of the 68 involved eyes (66%) had 20/40 visual acuity or better. Choroidal neovascularization (CNV) developed within choroiditis lesions in 22 (19 patients) of 68 eyes, causing visual acuity poorer than 20/50 in 14 eyes. The final average visual acuity in patients with PIC was 20/39; 23 (77%) of the 30 involved eyes had visual acuity of 20/40 or better. Six of the seven eyes with 20/50 or poorer vision had CNV. Six other eyes had CNV within the macula that regressed spontaneously with good resultant vision. Seven of the ten involved eyes with DSF syndrome had 20/200 or poorer vision. Poor vision was due to fibrosis and atrophy within the macula. Most patients with MCP and PIC retained visual acuity of 20/40 or better. In nearly one third of patients with MCP and PIC, CNV developed. Severe visual loss in these diseases was usually due to subfoveal CNV. Patients with DSF syndrome had a poor prognosis due to fibrosis and atrophy involving the macula.

Retina - drug effects

Prognosis

Choroid Diseases - complications

Humans

Retina - physiopathology

Choroid - blood supply

Neovascularization, Pathologic - surgery

Choroiditis - complications

Male

Laser Coagulation

Adrenal Cortex Hormones - therapeutic use

Visual Acuity

Neovascularization, Pathologic - etiology

Syndrome

Choroiditis - drug therapy

Choroid Diseases - drug therapy

Fibrosis

Choroiditis - physiopathology

Adult

Female

Choroid Diseases - physiopathology

Fundus Oculi

Retina - pathology

Fluorescein Angiography

Details

Title: Subtitle: Visual prognosis of multifocal choroiditis, punctate inner choroidopathy, and the diffuse subretinal fibrosis syndrome
Creators: Jeremiah Brown Jr - Department of Ophthalmology, University of Iowa Hospitals and Clinics, Iowa City 52240, USA
James C Folk
Chittaranjan V Reddy
Alan E Kimura
Resource Type: Journal article
Publication Details: Ophthalmology (Rochester, Minn.), Vol.103(7), pp.1100-1105
Publisher: Elsevier; United States
DOI: 10.1016/S0161-6420(96)30561-7
PMID: 8684800
ISSN: 0161-6420
eISSN: 1549-4713
Language: English
Date published: 07/1996
Academic Unit: Ophthalmology and Visual Sciences
Record Identifier: 9983979916102771

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