Journal article
Vitamin D Deficiency in Cystic Fibrosis
International Journal of Endocrinology, Vol.2010, 218691
01/28/2010
DOI: 10.1155/2010/218691
PMCID: PMC2817861
PMID: 20148079
Abstract
Cystic Fibrosis is the most common inherited genetic respiratory disorder in the Western World. Hypovitaminosis D is almost universal in CF patients, likely due to a combination of inadequate absorption, impaired metabolism, and lack of sun exposure. Inadequate levels are associated with the high prevalence of bone disease or osteoporosis in CF patients, which is associated with increased morbidity including fractures, kyphosis, and worsening pulmonary status. Treatment goals include regular monitoring 25 hydroxyvitamin D (25OHD) levels with aggressive treatment for those with levels <75 nmol/L (<30 ng/mL). More research is needed to determine optimal supplementation goals and strategies.
Details
- Title: Subtitle
- Vitamin D Deficiency in Cystic Fibrosis
- Creators
- William B Hall - University of North Carolina at Chapel HillAmy A Sparks - University of Iowa, Obstetrics and GynecologyRobert M Aris - University of North Carolina at Chapel Hill
- Resource Type
- Journal article
- Publication Details
- International Journal of Endocrinology, Vol.2010, 218691
- DOI
- 10.1155/2010/218691
- PMID
- 20148079
- PMCID
- PMC2817861
- NLM abbreviation
- Int J Endocrinol
- ISSN
- 1687-8337
- eISSN
- 1687-8345
- Publisher
- Hindawi Publishing Corporation
- Grant note
- DOI: 10.13039/100009993, name: Clinical Translational Research Center, award: 1U54RR024383, 5T32HL007106-33
- Language
- English
- Date published
- 01/28/2010
- Academic Unit
- Obstetrics and Gynecology
- Record Identifier
- 9983557490602771
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