Journal article
Vitamin D Receptor (VDR) and Group-Specific Component (GC, Vitamin D–Binding Protein) Polymorphisms in Myopia
Investigative ophthalmology & visual science, Vol.52(6), pp.3818-3824
05/2011
DOI: 10.1167/iovs.10-6534
PMCID: PMC3109057
PMID: 21357399
Abstract
The protective effect of time outdoors in lowering the risk of myopia onset suggests that vitamin D metabolism may be altered in myopia. This study provides evidence that genetic variants within the vitamin D receptor gene
VDR
may be associated with myopia in white subjects with milder levels of myopia. Replication is needed, as well as establishing whether there is any biological relevance of these variations to myopia.
Details
- Title: Subtitle
- Vitamin D Receptor (VDR) and Group-Specific Component (GC, Vitamin D–Binding Protein) Polymorphisms in Myopia
- Creators
- Donald O Mutti - From theMargaret E Cooper - theEcaterina Dragan - theLisa A Jones-Jordan - From theMelissa D Bailey - From theMary L Marazita - theJeffrey C Murray - theKarla Zadnik - From the
- Resource Type
- Journal article
- Publication Details
- Investigative ophthalmology & visual science, Vol.52(6), pp.3818-3824
- DOI
- 10.1167/iovs.10-6534
- PMID
- 21357399
- PMCID
- PMC3109057
- NLM abbreviation
- Invest Ophthalmol Vis Sci
- ISSN
- 0146-0404
- eISSN
- 1552-5783
- Publisher
- Association for Research in Vision and Ophthalmology, Inc
- Grant note
- U10-EY08893; R24-EY014792 / National Institutes of Health
- Language
- English
- Date published
- 05/2011
- Academic Unit
- Anatomy and Cell Biology; Stead Family Department of Pediatrics; Epidemiology; Pediatric Dentistry; Craniofacial Anomalies Research Center; Dental Research
- Record Identifier
- 9984025311902771
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