Journal article
Vitamin and trace element deficiencies in the pediatric dialysis patient
Pediatric nephrology (Berlin, West), Vol.33(7), pp.1133-1143
07/2018
DOI: 10.1007/s00467-017-3751-z
PMCID: PMC5787050
PMID: 28752387
Abstract
Pediatric dialysis patients are at risk of nutritional illness secondary to deficiencies in water-soluble vitamins and trace elements. Unlike 25-OH vitamin D, most other vitamins and trace elements are not routinely monitored in the blood and, consequently, the detection of any deficiency may not occur until significant complications develop. Causes of vitamin and trace element deficiency in patients on maintenance dialysis patient are multifactorial, ranging from diminished nutritional intake to altered metabolism as well as dialysate-driven losses of water-soluble vitamins and select trace elements. In this review we summarize the nutritional sources of key water-soluble vitamins and trace elements with a focus on the biological roles and clinical manifestations of their respective deficiency to augment awareness of potential nutritional illness in pediatric patients receiving maintenance dialysis. The limited pediatric data on the topic of clearance of water-soluble vitamins and trace elements by individual dialysis modality are reviewed, including a brief discussion on clearance of water-soluble vitamins and trace elements with continuous renal replacement therapy.
Details
- Title: Subtitle
- Vitamin and trace element deficiencies in the pediatric dialysis patient
- Creators
- Lyndsay A Harshman - Stead Family Department of Pediatrics, University of Iowa Hospitals and Clinics, 200 Hawkins Drive, 4037 Boyd Tower, Iowa City, IA, 52242-1053, USA. lyndsay-harshman@uiowa.eduKathy Lee-Son - Stead Family Department of Pediatrics, Division of Nephrology, Dialysis & Transplantation, University of Iowa Stead Family Children's Hospital, Iowa City, IA, USAJennifer G Jetton - Stead Family Department of Pediatrics, Division of Nephrology, Dialysis & Transplantation, University of Iowa Stead Family Children's Hospital, Iowa City, IA, USA
- Resource Type
- Journal article
- Publication Details
- Pediatric nephrology (Berlin, West), Vol.33(7), pp.1133-1143
- DOI
- 10.1007/s00467-017-3751-z
- PMID
- 28752387
- PMCID
- PMC5787050
- NLM abbreviation
- Pediatr Nephrol
- ISSN
- 0931-041X
- eISSN
- 1432-198X
- Publisher
- Germany
- Grant note
- K23 DK110443 / NIDDK NIH HHS
- Language
- English
- Date published
- 07/2018
- Academic Unit
- Nephrology, Dialysis and Transplantation; Stead Family Department of Pediatrics; Iowa Neuroscience Institute
- Record Identifier
- 9984065489802771
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