Journal article
Voice Outcomes Following Serial Office-Based Steroid Injections and Voice Therapy for Vocal Fold Scar
Journal of voice, Vol.39(5), pp.1377-1384
09/2025
DOI: 10.1016/j.jvoice.2023.02.036
PMID: 37076383
Abstract
Previous studies indicate that certain voice outcomes can improve following a single office-based steroid injection with voice therapy for vocal fold scar. We evaluated voice outcomes after a series of three timed office-based steroid injections with voice therapy.
Retrospective case series with chart review.
Academic medical center.
We evaluated pre-and postprocedural patient-reported, perceptual, acoustic, aerodynamic, and videostroboscopic parameters. We evaluated 23 patients who underwent three office-based dexamethasone injections into the superficial lamina propria one month apart. All patients pursued voice therapy.
Voice Handicap Index (n = 19; P= .030) decreased after injection series. Total GRBAS score (grade, roughness, breathiness, asthenia, strain) decreased (n = 23; P = 0.001). Dysphonia severity index score improved (n = 20; P = 0.041). Phonation threshold pressure did not decrease significantly (n = 22; P = 0.536). Videostroboscopic parameters of vocal fold edge (P = 0.023), right mucosal wave (P = 0.023) improved or normalized after injection series. Glottic closure (P = 0.134) did not improve.
Series of three office-based steroid injections combined with voice therapy for vocal fold scar does not appear to provide further benefit than one injection. Despite lack of improvements of PTP and other parameters, injection series is likewise unlikely to worsen dysphonia. A partially negative study provides value in investigation of less invasive treatment alternatives for a disorder that is challenging to treat. Future studies exploring effects of voice therapy alone without other intervention and consideration of sham injection versus steroid injection are warranted.
Details
- Title: Subtitle
- Voice Outcomes Following Serial Office-Based Steroid Injections and Voice Therapy for Vocal Fold Scar
- Creators
- Chelsea M Kruse - University of Wisconsin–MadisonMatthew R Hoffman - University of IowaBrienne N Hennessy - University of Wisconsin–MadisonStephen S Schoeff - Washington Permanente Medical Group, Tacoma, WashingtonSeth H Dailey - University of Wisconsin–Madison
- Resource Type
- Journal article
- Publication Details
- Journal of voice, Vol.39(5), pp.1377-1384
- DOI
- 10.1016/j.jvoice.2023.02.036
- PMID
- 37076383
- NLM abbreviation
- J Voice
- ISSN
- 0892-1997
- eISSN
- 1873-4588
- Language
- English
- Electronic publication date
- 04/17/2023
- Date published
- 09/2025
- Academic Unit
- Otolaryngology
- Record Identifier
- 9984398344502771
Metrics
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