Journal article
Voice Outcomes following a Single Office-Based Steroid Injection for Vocal Fold Scar
Otolaryngology-head and neck surgery, Vol.155(5), pp.820-828
11/2016
DOI: 10.1177/0194599816654899
PMID: 27507145
Abstract
Persistent dysphonia from vocal fold scar remains a clinical challenge, with current therapies providing inconsistent outcomes. We evaluated voice outcomes after a single office-based steroid injection.
Case series with chart review.
Academic medical center.
This study was based on pre- and postoperative analysis of patient-reported, perceptual, acoustic, aerodynamic, and videostroboscopic parameters. The sample comprised 25 patients undergoing office-based dexamethasone injection into the superficial lamina propria for mild/moderate vocal fold scar. Average follow-up was 13.7 ± 4.4 weeks; patients completed 3.5 ± 2.3 sessions of voice therapy between assessments. Complete data sets were not available for each parameter; sample size is noted with results.
Voice handicap index (n = 24; P < .001) and glottal function index (n = 22; P < .001) decreased after injection. Total GRBAS score (grade, roughness, breathiness, asthenia, strain) decreased (n = 25; P < .001). Fundamental frequency range increased (n = 24; P = .024). Phonation threshold pressure decreased (n = 14; P = .017). Videostroboscopic parameters of vocal fold edge (P = .004), glottic closure (P = .003), and right mucosal wave (P = .016) improved after injection.
Office-based steroid injection combined with voice therapy for mild/moderate vocal fold scar is associated with improved patient-reported and functional voice measures. These findings provide preliminary support for this approach. Importantly, the procedure is low risk and can be performed in the office, thus offering a simple treatment alternative to patients with a disorder that has traditionally been difficult to manage. Prospective studies evaluating the effects of multiple injections are warranted.
Details
- Title: Subtitle
- Voice Outcomes following a Single Office-Based Steroid Injection for Vocal Fold Scar
- Creators
- William G Young - University of Wisconsin–MadisonMatthew R Hoffman - University of Wisconsin–MadisonIan J Koszewski - University of Wisconsin–MadisonChad W Whited - University of Wisconsin–MadisonBrienne N Ruel - University of Wisconsin–MadisonSeth H Dailey - University of Wisconsin–Madison
- Resource Type
- Journal article
- Publication Details
- Otolaryngology-head and neck surgery, Vol.155(5), pp.820-828
- DOI
- 10.1177/0194599816654899
- PMID
- 27507145
- ISSN
- 0194-5998
- eISSN
- 1097-6817
- Language
- English
- Date published
- 11/2016
- Academic Unit
- Otolaryngology
- Record Identifier
- 9984366375002771
Metrics
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