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Von Recklinghausen neurofibromatosis: a linkage study of candidate and random marker genes
Journal article   Open access   Peer reviewed

Von Recklinghausen neurofibromatosis: a linkage study of candidate and random marker genes

Robert E Ferrell, Kenneth H Buetow, John K Darby, June E Eichner, Jeffrey C Murray, R Smith, Mary Waziri, Susan Huson and Vincent M Riccardi
Journal of medical genetics, Vol.24(9), pp.522-524
09/1987
DOI: 10.1136/jmg.24.9.522
PMID: 3118028
url
https://doi.org/10.1136/jmg.24.9.522View
Published (Version of record) Open Access

Abstract

Genotyping, using plasma proteins or DNA polymorphisms or both, was carried out on 30 families selected through probands with Von Recklinghausen disease. The data provide additional evidence for the exclusion of loci on chromosomes 3 and 5, and chromosome arms 1q, 2p, 4p, 4q, 6q, 7p, 9q, 11p, 11q, and 14q. There was no evidence for genetic heterogeneity at D1S1 (DNF15S2) on chromosome arm 3p, using the Morton test for heterogeneity.

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