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Vulvar Intraepithelial Neoplasia (VIN) and Condylomata
Journal article   Peer reviewed

Vulvar Intraepithelial Neoplasia (VIN) and Condylomata

Erin L Nelson, Fabrizio Bogliatto and Colleen K Stockdale
Clinical obstetrics and gynecology, Vol.58(3), pp.512-525
09/2015
DOI: 10.1097/GRF.0000000000000132
PMID: 26133495

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Abstract

Human papillomavirus (HPV) infection of the lower genital tract is common and its effects are variable. The majority of infections are transient and the related pathology is self-resolving. Condyloma accuminatum is caused predominantly by HPV 6, 11 and can be managed with medical or surgical therapy. Vulvar intraepithelial neoplasia is a treatable precursor to vulvar cancer with 2 main forms: one related to HPV and the other to chronic vulvar inflammatory conditions. It may be treated medically, surgically, or potentially via the use of therapeutic HPV vaccines. Preventive utilization of a quadrivalent HPV vaccine has the potential to decrease HPV-related lower genital disease burden substantially.
 Condylomata Acuminata - therapy Precancerous Conditions - epidemiology Papillomavirus Vaccines - therapeutic use Precancerous Conditions - therapy Carcinoma, Squamous Cell - epidemiology Humans Papillomavirus Infections - epidemiology Carcinoma, Squamous Cell - therapy Condylomata Acuminata - epidemiology Carcinoma in Situ - therapy Papillomavirus Infections - diagnosis Papillomavirus Infections - therapy Carcinoma, Squamous Cell - diagnosis Condylomata Acuminata - diagnosis Vulvar Neoplasms - therapy Precancerous Conditions - diagnosis Carcinoma in Situ - epidemiology Vulvar Neoplasms - epidemiology Female Vulvar Neoplasms - diagnosis Carcinoma in Situ - diagnosis

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