Journal article
Watching Small Vessel Disease Grow
Circulation research, Vol.122(6), pp.810-812
03/16/2018
DOI: 10.1161/CIRCRESAHA.118.312762
PMCID: PMC5926815
PMID: 29700083
Abstract
Cerebrovascular disease is a major contributor to loss of brain health, a leading medical, societal, and financial issue worldwide. 1 Although ischemic and hemorrhagic strokes are widely known end-organ effects, diseases of the cerebral circulation are important contributors to mild cognitive deficits, dementia, and an array of neurological and psychiatric disorders. 2,3 Of the risk factors for large and small vessel disease (SVD), aging, and hypertension lead the way, with genetic, metabolic, and behavioral contributors and modifiers (Figure). This Viewpoint briefly highlights features of SVD, its impact on brain health, emerging evidence SVD contributes to diseases not thought to have a cerebrovascular basis, and some suggestions as the field moves forward.
Details
- Title: Subtitle
- Watching Small Vessel Disease Grow
- Creators
- Frank M. Faraci - University of Iowa
- Resource Type
- Journal article
- Publication Details
- Circulation research, Vol.122(6), pp.810-812
- DOI
- 10.1161/CIRCRESAHA.118.312762
- PMID
- 29700083
- PMCID
- PMC5926815
- NLM abbreviation
- Circ Res
- ISSN
- 0009-7330
- eISSN
- 1524-4571
- Publisher
- Lippincott Williams & Wilkins
- Number of pages
- 3
- Grant note
- R01HL113863 / NATIONAL HEART, LUNG, AND BLOOD INSTITUTE; United States Department of Health & Human Services; National Institutes of Health (NIH) - USA; NIH National Heart Lung & Blood Institute (NHLBI) Fondation Leducq; Leducq Foundation R01NS096465 / NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND STROKE; United States Department of Health & Human Services; National Institutes of Health (NIH) - USA; NIH National Institute of Neurological Disorders & Stroke (NINDS) BX001399 / Department of Veteran's Affair's; US Department of Veterans Affairs HL113863; NS096465 / National Institutes of Health; United States Department of Health & Human Services; National Institutes of Health (NIH) - USA I01BX001399 / Veterans Affairs; US Department of Veterans Affairs
- Language
- English
- Date published
- 03/16/2018
- Academic Unit
- Cardiovascular Medicine; Neuroscience and Pharmacology; Internal Medicine
- Record Identifier
- 9984303743902771
Metrics
5 Record Views