Journal article
Weight loss after head and neck cancer: A dynamic relationship with depressive symptoms
Head & neck, Vol.39(2), pp.370-379
02/01/2017
DOI: 10.1002/hed.24601
PMCID: PMC5771807
PMID: 27704695
Abstract
Background. Weight loss and depressive symptoms are critical head and neck cancer outcomes, yet their relation over the illness course is unclear.
Methods. Associations between self-reported depressive symptoms and objective weight loss across the year after head and neck cancer diagnosis were examined using growth curve modeling techniques (n = 564).
Results. A reciprocal covariation pattern emerged-changes in depressive symptoms over time were associated with same-month changes in weight loss (t [1148] = 2.05; p = .041), and changes in weight loss were associated with same-month changes in depressive symptoms (t [556] = 2.43; p = .015). To the extent that depressive symptoms increased, patients lost incrementally more weight than was lost due to the passage of time and vice versa. Results also suggested that pain and eating-related quality of life might explain the reciprocal association between depressive symptoms and weight loss.
Conclusion. In head and neck cancer, a transactional interplay between depressive symptoms and weight loss unfolds over time. (C) 2016 Wiley Periodicals, Inc.
Details
- Title: Subtitle
- Weight loss after head and neck cancer: A dynamic relationship with depressive symptoms
- Creators
- Julia R. Van Liew - University of IowaRebecca L. Brock - University of Nebraska–LincolnAlan J. Christensen - University of IowaLucy Hynds Karnell - University of IowaNitin A. Pagedar - University of IowaGerry F. Funk - Grande Ronde Hospital
- Resource Type
- Journal article
- Publication Details
- Head & neck, Vol.39(2), pp.370-379
- DOI
- 10.1002/hed.24601
- PMID
- 27704695
- PMCID
- PMC5771807
- NLM abbreviation
- Head Neck
- ISSN
- 1043-3074
- eISSN
- 1097-0347
- Publisher
- Wiley
- Number of pages
- 10
- Grant note
- DP2OD007483 / OFFICE OF THE DIRECTOR, NATIONAL INSTITUTES OF HEALTH; United States Department of Health & Human Services; National Institutes of Health (NIH) - USA R01 CA106908 / National Institutes of Health through the Office of Cancer Survivorship R01CA106908 / NATIONAL CANCER INSTITUTE; United States Department of Health & Human Services; National Institutes of Health (NIH) - USA; NIH National Cancer Institute (NCI)
- Language
- English
- Date published
- 02/01/2017
- Academic Unit
- Psychological and Brain Sciences; Otolaryngology
- Record Identifier
- 9984312244202771
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