Journal article
What causes spasm of atherosclerotic arteries? Is regression of plaques beneficial?
Transactions of the American Clinical and Climatological Association, Vol.101, pp.103-113
1990
PMCID: PMC2376490
PMID: 2486435
Abstract
We would like to emphasize three points. First, atherosclerosis produces a profound alteration of vascular responses, which may lead to spasm in several vascular beds. Second, we have proposed that leukocytes as well as platelets may play a critical role in the pathophysiology of vasospasm. Third, there is bad news and good news in relation to regression of atherosclerosis. Maximal vasodilator capacity does not improve consistently during regression of atherosclerosis, but endothelium-dependent relaxation improves, hypersensitivity of blood vessels subsides, and we speculate that susceptibility to vasospasm may be abolished.
Details
- Title: Subtitle
- What causes spasm of atherosclerotic arteries? Is regression of plaques beneficial?
- Creators
- Donald D Heistad - Department of Internal Medicine, Veterans Administration Medical Center, Iowa City, IAMark L Armstrong - Department of Internal Medicine, Veterans Administration Medical Center, Iowa City, IAJ. Antonio G. Lopez - Department of Internal Medicine, Veterans Administration Medical Center, Iowa City, IA
- Resource Type
- Journal article
- Publication Details
- Transactions of the American Clinical and Climatological Association, Vol.101, pp.103-113
- Publisher
- American Clinical and Climatological Association
- PMID
- 2486435
- PMCID
- PMC2376490
- ISSN
- 0065-7778
- Language
- English
- Date published
- 1990
- Academic Unit
- Cardiovascular Medicine; Neuroscience and Pharmacology; Internal Medicine
- Record Identifier
- 9984040469302771
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