Widespread Pain Moderates the Response to Centrally‐Acting Therapies in an Observational Cohort of Patients With Urologic Chronic Pelvic Pain Syndrome: A MAPP Research Network Study

Andrew Schrepf; Kenneth Locke; Robert Moldwin; David A. Williams; Sara Till; John Farrar; J Richard Landis; Frank Tu; Larissa Rodriguez; Henry Lai; Bruce Naliboff; Jason Kutch; Steven E. Harte; Richard E. Harris; Karl J. Kreder; Tracy Spitznagle; Lindsey McKernan; Claire Yang; J Quentin Clemens; Chris Mullins; Daniel J. Clauw

doi:10.1002/nau.70068

Back

Widespread Pain Moderates the Response to Centrally‐Acting Therapies in an Observational Cohort of Patients With Urologic Chronic Pelvic Pain Syndrome: A MAPP Research Network Study

Journal article

Open access

Peer reviewed

Widespread Pain Moderates the Response to Centrally‐Acting Therapies in an Observational Cohort of Patients With Urologic Chronic Pelvic Pain Syndrome: A MAPP Research Network Study

Andrew Schrepf, Kenneth Locke, Robert Moldwin, David A. Williams, Sara Till, John Farrar, J Richard Landis, Frank Tu, Larissa Rodriguez, Henry Lai, …

Neurourology and urodynamics, Vol.44(6), pp.1290-1295

08/2025

DOI: 10.1002/nau.70068

PMCID: PMC12264457

PMID: 40415481

Files and links (1)

url

https://doi.org/10.1002/nau.70068View

Published (Version of record) Open Access

Abstract

Widespread pain is associated with a better treatment response to centrally‐acting medicines in Urologic Chronic Pelvic Pain Syndrome.

Chronic Pain

amitriptyline

interstitial cystitis

pelvic floor

prostatitis

Details

Title: Subtitle: Widespread Pain Moderates the Response to Centrally‐Acting Therapies in an Observational Cohort of Patients With Urologic Chronic Pelvic Pain Syndrome: A MAPP Research Network Study
Creators: Andrew Schrepf - University of Michigan
Kenneth Locke - University of Pennsylvania
Robert Moldwin - Hofstra University
David A. Williams - University of Michigan
Sara Till - University of Michigan
John Farrar - University of Pennsylvania
J Richard Landis - University of Pennsylvania
Frank Tu - NorthShore University HealthSystem
Larissa Rodriguez - Weill Cornell Medicine
Henry Lai - Washington University School of Medicine St Louis Missouri USA
Bruce Naliboff - University of California, Los Angeles
Jason Kutch - University of Southern California
Steven E. Harte - University of Michigan
Richard E. Harris - University of California, Irvine
Karl J. Kreder - University of Iowa
Tracy Spitznagle - Washington University in St. Louis
Lindsey McKernan - Vanderbilt University
Claire Yang - University of Washington
J Quentin Clemens - University of Michigan
Chris Mullins - National Institute of Diabetes and Digestive and Kidney Diseases
Daniel J. Clauw - University of Michigan
Resource Type: Journal article
Publication Details: Neurourology and urodynamics, Vol.44(6), pp.1290-1295
DOI: 10.1002/nau.70068
PMID: 40415481
PMCID: PMC12264457
NLM abbreviation: Neurourol Urodyn
ISSN: 0733-2467
eISSN: 1520-6777
Publisher: Wiley
Grant note: Funding for the MAPP Research Network was obtained under a cooperative agreement from National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), National Institutes of Health (NIH) (DK82370, DK82342, DK82315, DK82344, DK82325, DK82345, DK823National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK): DK82370, DK82342, DK82315, DK82344, DK82325, DK82345, DK82333, DK82316 National Institutes of Health (NIH)
Funding for the MAPP Research Network was obtained under a cooperative agreement from National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), National Institutes of Health (NIH) (DK82370, DK82342, DK82315, DK82344, DK82325, DK82345, DK82333, and DK82316).
Language: English
Electronic publication date: 05/25/2025
Date published: 08/2025
Academic Unit: Obstetrics and Gynecology; Urology
Record Identifier: 9984825526002771

Metrics

2 Record Views

2 Times Cited - Web of Science

See more details