Journal article
Wingspan experience in the treatment of symptomatic intracranial atherosclerotic disease after antithrombotic failure
Journal of neurointerventional surgery, Vol.5(4), pp.302-305
07/2013
DOI: 10.1136/neurintsurg-2012-010321
PMID: 22544819
Abstract
Background and purpose Intracranial stenting with the Wingspan system has been used as a revascularization strategy in symptomatic patients with intracranial atherosclerotic disease (ICAD). The latest results of the Stenting versus Aggressive Medical Therapy for Intracranial Artery Stenosis (SAMMPRIS) trial challenge this approach. Our experience in the treatment of symptomatic ICAD with the Wingspan system is reported. Materials and methods Patients who underwent stenting for symptomatic ICAD were included in the analysis. Demographic data, periprocedural complications, long term radiological and clinical outcomes are reported. Results 46 lesions were treated in 45 patients. 13 patients (29%) presented with a transient ischemic attack and 32 (71%) with a stroke. 43 patients (95.5%) failed antithrombotic therapy at presentation. One (2%) symptomatic periprocedural (24 h) complication occurred. The 30 day incidence of stroke and vascular death was 6.6%—a fatal hemorrhagic stroke and two non-fatal hemorrhagic strokes. In-stent stenosis (≥50%) was seen in nine (42.8%) lesions, two were symptomatic. Conclusions This cohort of patients with symptomatic ICAD who failed antithrombotic medications benefited from angioplasty and stenting with the Wingspan system.
Details
- Title: Subtitle
- Wingspan experience in the treatment of symptomatic intracranial atherosclerotic disease after antithrombotic failure
- Creators
- Edgar A Samaniego - Department of Neurointerventional Surgery, Baptist Neuroscience Center, Miami, FL, USAFrancesca Tari-Capone - Department of Neuroscience, Mental Health and Sensory Organs, University of Rome ‘La Sapienza’, Rome, ItalyItalo Linfante - Department of Neurointerventional Surgery, Baptist Neuroscience Center, Miami, FL, USAChristine F Silva - Department of Radiology, New England Center for Stroke Research, University of Massachusetts Medical School, Worcester, MA, USAGabriela Spilberg - Department of Radiology, New England Center for Stroke Research, University of Massachusetts Medical School, Worcester, MA, USAMatthew Gounis - Department of Radiology, New England Center for Stroke Research, University of Massachusetts Medical School, Worcester, MA, USAAjay K Wakhloo - Department of Radiology, New England Center for Stroke Research, University of Massachusetts Medical School, Worcester, MA, USAGuilherme Dabus - Department of Neurointerventional Surgery, Baptist Neuroscience Center, Miami, FL, USA
- Resource Type
- Journal article
- Publication Details
- Journal of neurointerventional surgery, Vol.5(4), pp.302-305
- DOI
- 10.1136/neurintsurg-2012-010321
- PMID
- 22544819
- ISSN
- 1759-8478
- eISSN
- 1759-8486
- Language
- English
- Date published
- 07/2013
- Academic Unit
- Neurology; Radiology; Iowa Neuroscience Institute; Neurosurgery
- Record Identifier
- 9984020622002771
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