Journal article
Withania somnifera Improves Semen Quality in Stress-Related Male Fertility
Evidence-based complementary and alternative medicine, Vol.2011(2011), pp.1-9
01/01/2011
DOI: 10.1093/ecam/nep138
PMCID: PMC3136684
PMID: 19789214
Abstract
Stress has been reported to be a causative factor for male infertility. Withania somnifera has been documented in Ayurveda and Unani medicine system for its stress-combating properties. However, limited scientific literature is available on this aspect of W. somnifera. We undertook the present study to understand the role of stress in male infertility, and to test the ability of W. somnifera to combat stress and treat male infertility. We selected normozoospermic but infertile individuals (N = 60), further categorized in three groups: normozoospermic heavy smokers (N = 20), normozoospermics under psychological stress (N = 20) and normozoospermics with infertility of unknown etiology (N = 20). Normozoospermic fertile men (N = 60) were recruited as controls. The subjects were given root powder of W. somnifera at a rate of 5 g/day for 3 months. Measuring various biochemical and stress parameters before and after treatment, suggested a definite role of stress in male infertility and the ability of W. somnifera to treat stress-related infertility. Treatment resulted in a decrease in stress, improved the level of anti-oxidants and improved overall semen quality in a significant number of individuals. The treatment resulted in pregnancy in the partners of 14% of the patients.
Details
- Title: Subtitle
- Withania somnifera Improves Semen Quality in Stress-Related Male Fertility
- Creators
- Abbas Ali Mahdi - King George's Medical UniversityKamla Kant Shukla - King George's Medical UniversityMohammad Kaleem Ahmad - King George's Medical UniversitySingh Rajender - Central Drug Research InstituteSatya Narain Shankhwar - King George's Medical UniversityVishwajeet Singh - King George's Medical UniversityDeepansh Dalela - King George's Medical University
- Resource Type
- Journal article
- Publication Details
- Evidence-based complementary and alternative medicine, Vol.2011(2011), pp.1-9
- DOI
- 10.1093/ecam/nep138
- PMID
- 19789214
- PMCID
- PMC3136684
- NLM abbreviation
- Evid Based Complement Alternat Med
- ISSN
- 1741-427X
- eISSN
- 1741-4288
- Publisher
- Hindawi Publishing Group
- Number of pages
- 9
- Grant note
- 5/10/8/2004-RHN / Indian Council of Medical Research, New Delhi, India; Indian Council of Medical Research (ICMR)
- Language
- English
- Date published
- 01/01/2011
- Academic Unit
- Urology
- Record Identifier
- 9984949175702771
Metrics
6 Record Views