Work, leisure-time physical activity, and risk of preeclampsia and gestational hypertension

Audrey F Saftlas; Nyla Logsden-Sackett; Wenquan Wang; Robert Woolson; Michael B Bracken

doi:10.1093/aje/kwh277

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Work, leisure-time physical activity, and risk of preeclampsia and gestational hypertension

Journal article

Open access

Peer reviewed

Work, leisure-time physical activity, and risk of preeclampsia and gestational hypertension

Audrey F Saftlas, Nyla Logsden-Sackett, Wenquan Wang, Robert Woolson and Michael B Bracken

American journal of epidemiology, Vol.160(8), pp.758-765

10/15/2004

DOI: 10.1093/aje/kwh277

PMID: 15466498

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Abstract

Few studies of preeclampsia have assessed physical activity level, yet recent evidence suggests that the pathologic mechanisms in preeclampsia are similar to those in cardiovascular disease, for which physical activity is shown to be protective. The authors assessed the independent and combined effects of work and regular leisure-time physical activity (LTPA) during early pregnancy on risk of de novo preeclampsia (n = 44) and gestational hypertension (n = 172) among women recruited from 13 obstetric practices in the New Haven, Connecticut, area between 1988 and 1991. Control subjects were normotensive throughout pregnancy (n = 2,422). Information on time at work spent sitting, standing, and walking and on LTPA before and during pregnancy was collected via face-to-face interviews. Logistic regression analyses suggested that women who engaged in any regular LTPA regardless of caloric expenditure (adjusted odds ratio (aOR) = 0.66, 95% confidence interval (CI): 0.35, 1.22), were unemployed (aOR = 0.64, 95% CI: 0.21, 2.00), or had nonsedentary jobs (aOR = 0.71, 95% CI: 0.37, 1.36) were at decreased risk of preeclampsia. Analyses of gestational hypertension showed no indication of a protective effect of workplace activity, LTPA, or unemployment. Consistent with other studies, these data suggest that regular physical activity during pregnancy may reduce preeclampsia risk.

Adult

Case-Control Studies

Confounding Factors (Epidemiology)

Connecticut - epidemiology

Employment - statistics & numerical data

Energy Metabolism

Exercise

Female

Humans

Hypertension - epidemiology

Hypertension - etiology

Hypertension - prevention & control

Leisure Activities

Logistic Models

Pre-Eclampsia - epidemiology

Pre-Eclampsia - etiology

Pre-Eclampsia - prevention & control

Pregnancy

Recurrence

Risk Factors

Surveys and Questionnaires

Time and Motion Studies

Urban Health - statistics & numerical data

Details

Title: Subtitle: Work, leisure-time physical activity, and risk of preeclampsia and gestational hypertension
Creators: Audrey F Saftlas - University of Iowa
Nyla Logsden-Sackett
Wenquan Wang
Robert Woolson
Michael B Bracken
Resource Type: Journal article
Publication Details: American journal of epidemiology, Vol.160(8), pp.758-765
DOI: 10.1093/aje/kwh277
PMID: 15466498
ISSN: 0002-9262
eISSN: 1476-6256
Grant note: R01 DA05484 / NIDA NIH HHS R01 HD32579 / NICHD NIH HHS R01 AI41040 / NIAID NIH HHS
Language: English
Date published: 10/15/2004
Academic Unit: Statistics and Actuarial Science; Epidemiology; Biostatistics
Record Identifier: 9984364440302771

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