Journal article
in vitro NMR characterization of mammalian myocardium: Effect of specimen integrity on relaxation times
Magnetic resonance in medicine, Vol.11(3), pp.367-370
09/1989
DOI: 10.1002/mrm.1910110310
PMID: 2674601
Abstract
We systematically evaluated three different methods of preparing canine myocardium for NMR relaxometry: using whole specimens, specimens sliced into approximately 2-mm3 pieces, and specimens minced into pieces less than 2 mm3. NMR relaxation times were determined at 20 MHz. T1 relaxation time and water content were not different among the three methods. However, T2 values differed significantly between whole and sliced samples (mean +/- SEM = 51.2 +/- 2.2 ms (whole) vs 54.3 +/- 2.7 ms (sliced): P less than 0.05). Minced myocardium showed a similar increase that was not statistically significant. We conclude that tissue preparation methods must be controlled when performing NMR relaxometry studies.
Details
- Title: Subtitle
- in vitro NMR characterization of mammalian myocardium: Effect of specimen integrity on relaxation times
- Creators
- Thomas D Scholz - Cardiovascular Center and Departments of Pediatrics, Internal Medicine, and Electrical and Computer Engineering, University of Iowa, Iowa City, Iowa 52242Steven R Fleagle - Cardiovascular Center and Departments of Pediatrics, Internal Medicine, and Electrical and Computer Engineering, University of Iowa, Iowa City, Iowa 52242David J Skorton - Cardiovascular Center and Departments of Pediatrics, Internal Medicine, and Electrical and Computer Engineering, University of Iowa, Iowa City, Iowa 52242
- Resource Type
- Journal article
- Publication Details
- Magnetic resonance in medicine, Vol.11(3), pp.367-370
- Publisher
- Wiley Subscription Services, Inc., A Wiley Company
- DOI
- 10.1002/mrm.1910110310
- PMID
- 2674601
- ISSN
- 0740-3194
- eISSN
- 1522-2594
- Number of pages
- 4
- Language
- English
- Date published
- 09/1989
- Academic Unit
- Cardiology; Stead Family Department of Pediatrics; Fraternal Order of Eagles Diabetes Research Center; Child and Community Health
- Record Identifier
- 9984093344602771
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