Journal article
microRNAs: Emerging players in oral cancers and inflammatory disorders
Tumor biology, Vol.39(5), pp.1-12
05/01/2017
DOI: 10.1177/1010428317698379
PMID: 28459366
Abstract
Association of oral diseases and disorders with altered microRNA profiles is firmly recognized. These evidences support the potential use of microRNAs as therapeutic tools for diagnosis, prognosis, and treatment of various diseases. In this review, we highlight the association of altered microRNA signatures in oral cancers and oral inflammatory diseases. Advances in our ability to detect microRNAs in human sera and saliva further highlight their clinical value as potential biomarkers. We have discussed key mechanisms underlying microRNA dysregulation in pathological conditions. The use of microRNAs in diagnostics and their potential therapeutic value in the treatment of oral diseases are reviewed.
Details
- Title: Subtitle
- microRNAs: Emerging players in oral cancers and inflammatory disorders
- Creators
- Varun Kulkarni - University of Illinois ChicagoJuhi Raju Uttamani - University of Illinois ChicagoAfsar Raza Naqvi - University of Illinois ChicagoSalvador Nares - University of Illinois Chicago
- Resource Type
- Journal article
- Publication Details
- Tumor biology, Vol.39(5), pp.1-12
- DOI
- 10.1177/1010428317698379
- PMID
- 28459366
- NLM abbreviation
- Tumour Biol
- ISSN
- 1010-4283
- eISSN
- 1423-0380
- Publisher
- Sage
- Number of pages
- 12
- Grant note
- University of Illinois at Chicago Edward C. Wach Fund DE021052 / NIH/NIDCR; United States Department of Health & Human Services; National Institutes of Health (NIH) - USA; NIH National Institute of Dental & Craniofacial Research (NIDCR)
- Language
- English
- Date published
- 05/01/2017
- Academic Unit
- Periodontics
- Record Identifier
- 9984367720402771
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