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Fndc5 is translated from an upstream ATG start codon and cleaved to produce irisin myokine precursor protein in humans and mice
Letter/Communication

Fndc5 is translated from an upstream ATG start codon and cleaved to produce irisin myokine precursor protein in humans and mice

Nathan H Witmer, Connor R Linzer and Ryan L Boudreau
Cell metabolism, Vol.36(5), pp.879-881
03/06/2024
DOI: 10.1016/j.cmet.2024.02.008
PMCID: PMC11555857
PMID: 38471509

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Abstract

Witmer et al. provide genomic and molecular evidence to demonstrate that Fndc5 (irisin myokine precursor protein) is translated in humans from an overlooked upstream ATG codon.

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