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Is Caplacizumab Effective in All Patients with iTTP?
Letter/Communication

Is Caplacizumab Effective in All Patients with iTTP?

Anjali Sharathkumar
NEJM journal watch. Oncology & hematology
08/29/2024

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Abstract

In a post-hoc analysis of the HERCULES trial, caplacizumab, a nanobody that inhibits von Willebrand factor–platelet interaction, demonstrated efficacy regardless of iTTP history, disease severity, or initial immunosuppression regimen, but questions remain about long-term remission.
Steroids Purpura

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