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Ivacaftor-Induced Proteomic Changes Suggest Monocyte Defects May Contribute to the Pathogenesis of Cystic Fibrosis
Letter/Communication   Open access

Ivacaftor-Induced Proteomic Changes Suggest Monocyte Defects May Contribute to the Pathogenesis of Cystic Fibrosis

Katherine B Hisert, Kelly Q Schoenfelt, Gordon Cooke, Brenda Grogan, Jan L Launspach, Charles G Gallagher, Seamas C Donnelly, Michael J Welsh, Pradeep K Singh, Edward F McKone, …
American journal of respiratory cell and molecular biology, Vol.54(4), pp.594-599
04/2016
DOI: 10.1165/rcmb.2015-0322LE
PMCID: PMC4821059
PMID: 27035067
url
https://doi.org/10.1165/rcmb.2015-0322LEView
Published (Version of record) Open Access

Abstract

Cystic Fibrosis - immunology Animals Cystic Fibrosis - metabolism Humans Cystic Fibrosis - pathology Proteome - drug effects Cystic Fibrosis Transmembrane Conductance Regulator - metabolism Monocytes - immunology Quinolones - pharmacology Aminophenols - pharmacology

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