Riluzole likely lacks antidepressant efficacy in ketamine non-responders

Mark J Niciu; David A Luckenbaugh; Dawn F Ionescu; Erica M Richards; Jennifer L Vande Voort; Elizabeth D Ballard; Nancy E Brutsche; Maura L Furey; Carlos A Zarate Jr

doi:10.1016/j.jpsychires.2014.07.022

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Riluzole likely lacks antidepressant efficacy in ketamine non-responders

Letter/Communication

Open access

Riluzole likely lacks antidepressant efficacy in ketamine non-responders

Mark J Niciu, David A Luckenbaugh, Dawn F Ionescu, Erica M Richards, Jennifer L Vande Voort, Elizabeth D Ballard, Nancy E Brutsche, Maura L Furey and Carlos A Zarate Jr

Journal of psychiatric research, Vol.58, pp.197-199

11/2014

DOI: 10.1016/j.jpsychires.2014.07.022

PMCID: PMC4300112

PMID: 25139008

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http://doi.org/10.1016/j.jpsychires.2014.07.022View

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Abstract

Dose-Response Relationship, Drug

Excitatory Amino Acid Antagonists - therapeutic use

Follow-Up Studies

Humans

Middle Aged

Riluzole - therapeutic use

Adult

Female

Male

Treatment Outcome

Ketamine - therapeutic use

Depressive Disorder, Treatment-Resistant - drug therapy

Details

Title: Subtitle: Riluzole likely lacks antidepressant efficacy in ketamine non-responders
Creators: Mark J Niciu - National Institutes of Health, National Institute of Mental Health, Experimental Therapeutics and Pathophysiology Branch (ETPB), 10 Center Dr., Building 10/CRC, Room 7-5545, Bethesda, MD 20892, USA. Electronic address: mark.niciu@nih.gov
David A Luckenbaugh - National Institutes of Health, National Institute of Mental Health, Experimental Therapeutics and Pathophysiology Branch (ETPB), 10 Center Dr., Building 10/CRC, Room 7-5545, Bethesda, MD 20892, USA
Dawn F Ionescu - National Institutes of Health, National Institute of Mental Health, Experimental Therapeutics and Pathophysiology Branch (ETPB), 10 Center Dr., Building 10/CRC, Room 7-5545, Bethesda, MD 20892, USA
Erica M Richards - National Institutes of Health, National Institute of Mental Health, Experimental Therapeutics and Pathophysiology Branch (ETPB), 10 Center Dr., Building 10/CRC, Room 7-5545, Bethesda, MD 20892, USA
Jennifer L Vande Voort - National Institutes of Health, National Institute of Mental Health, Experimental Therapeutics and Pathophysiology Branch (ETPB), 10 Center Dr., Building 10/CRC, Room 7-5545, Bethesda, MD 20892, USA
Elizabeth D Ballard - National Institutes of Health, National Institute of Mental Health, Experimental Therapeutics and Pathophysiology Branch (ETPB), 10 Center Dr., Building 10/CRC, Room 7-5545, Bethesda, MD 20892, USA
Nancy E Brutsche - National Institutes of Health, National Institute of Mental Health, Experimental Therapeutics and Pathophysiology Branch (ETPB), 10 Center Dr., Building 10/CRC, Room 7-5545, Bethesda, MD 20892, USA
Maura L Furey - National Institutes of Health, National Institute of Mental Health, Experimental Therapeutics and Pathophysiology Branch (ETPB), 10 Center Dr., Building 10/CRC, Room 7-5545, Bethesda, MD 20892, USA
Carlos A Zarate Jr - National Institutes of Health, National Institute of Mental Health, Experimental Therapeutics and Pathophysiology Branch (ETPB), 10 Center Dr., Building 10/CRC, Room 7-5545, Bethesda, MD 20892, USA
Resource Type: Letter/Communication
Publication Details: Journal of psychiatric research, Vol.58, pp.197-199
DOI: 10.1016/j.jpsychires.2014.07.022
PMID: 25139008
PMCID: PMC4300112
NLM abbreviation: J Psychiatr Res
ISSN: 0022-3956
eISSN: 1879-1379
Publisher: England
Grant note: Z99 MH999999 / Intramural NIH HHS
Language: English
Date published: 11/2014
Academic Unit: Psychiatry; Iowa Neuroscience Institute
Record Identifier: 9984003981802771

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