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The activity and toxicity of low dose clofarabine against relapsed or refractory myeloma
Letter/Communication

The activity and toxicity of low dose clofarabine against relapsed or refractory myeloma

Geoffrey L. Uy, Michael H. Tomasson, Alisa Ruddell, John F. DiPersio and Ravi Vij
Haematologica (Roma), Vol.91(11), pp.1581-1582
11/01/2006
PMID: 17043015

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Abstract

Eight patients with refractory multiple myeloma were treated with clofarabine 4 mg/m(2)/day on days 1-5 of a 28 day cycle. No objective evidence of anti-myeloma activity was observed (median time to progression of 52 days). All patients experienced grade 3-4 neutropenia and a greater than 50% decrease in platelet counts during treatment.
Hematology Life Sciences & Biomedicine Science & Technology

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