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Tominersen in Adults with Manifest Huntington’s Disease
Letter/Communication

Tominersen in Adults with Manifest Huntington’s Disease

Peter McColgan, Alpa Thobhani, Lauren Boak, Scott Schobel, Alessia Nicotra, Giuseppe Palermo, Dylan Trundell, Julian Zhou, Valerie Schlegel, Patricia Sanwald Ducray, …
The New England journal of medicine, Vol.389(23), pp.2203-2205
12/07/2023
DOI: 10.1056/NEJMc2300400
PMID: 38055260

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Abstract

Tominersen and Huntington’s DiseaseA trial of tominersen, designed to slow Huntington’s disease progression by lowering levels of huntingtin protein, was stopped prematurely, and an ad hoc analysis of the results at week 69 was carried out.
Biomarkers Cerebrospinal fluid Huntingtin Hypotheses Proteins

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