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2-t-butyl-3 alkyl-5-(m-hydroxyphenyl)-1,3-oxazolidines having mydriatic effect
Patent   Open access

2-t-butyl-3 alkyl-5-(m-hydroxyphenyl)-1,3-oxazolidines having mydriatic effect

Ronald D Schoenwald and Du-shieng Chien
United States Patent and Trademark Office
09/12/1989
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2-t-butyl-3 alkyl-5-(m-hydroxyphenyl)-13-oxazolidines having myd216.55 kBDownloadView
PDM V1.0 Open Access

Abstract

An oxazolidine derivative of phenylephrine, and the non-toxic pharmaceutically acceptable salt forms thereof. The prodrug is much quicker absorbed across the cornea of the eye, does not induce the same unwanted side effects as phenylephrine, and can produce the same mydriatic effect as phenylephrine at dosage levels of approximately one-tenth the level of phenylephrine.

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