GB virus C (hepatitis G virus) E2 glycoprotein as an immunomodulatory agent

Jack T Stapleton; Nirjal Bhattarai; Jinhua Xiang; James H Mclinden

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GB virus C (hepatitis G virus) E2 glycoprotein as an immunomodulatory agent

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GB virus C (hepatitis G virus) E2 glycoprotein as an immunomodulatory agent

Jack T Stapleton, Nirjal Bhattarai, Jinhua Xiang and James H Mclinden

United States Patent and Trademark Office

04/04/2017

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Abstract

GB virus C (GBV-C or hepatitis G virus) is a flavivirus that frequently leads to chronic viremia in humans. The invention provides compositions and methods involving GBV-C E2 polypeptides and peptides for use in modulating immune responses, including inhibition inflammation related to pathogenic T-cell activation.

Details

Title: Subtitle: GB virus C (hepatitis G virus) E2 glycoprotein as an immunomodulatory agent
Creators: Jack T Stapleton (Inventor)
Nirjal Bhattarai (Inventor)
Jinhua Xiang (Inventor)
James H Mclinden (Inventor)
Contributors: University of Iowa Research Foundation (Iowa City, IA, US) (Assignee)
The United States of America, as represented by the Department of Veterans Affairs (Washington, DC, US) (Assignee)
Resource Type: Patent
Publisher: United States Patent and Trademark Office; United States
Patent: US Patent 9,611,301; United States Patent and Trademark Office (United States, Alexandria) - USPTO; Published; 14/384,775; 03/13/2013
Number of pages: 87 pages
Language: English
Date published: 04/04/2017
Academic Unit: UI Research Foundation; Microbiology and Immunology; Internal Medicine
Record Identifier: 9983761961402771

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