Sign in
Immunostimulatory nucleic acid molecules
Patent   Open access

Immunostimulatory nucleic acid molecules

Arthur M Krieg and Joel N Kline
United States Patent and Trademark Office
05/03/2011
pdf
Immunostimulatory nucleic acid molecules765.19 kBDownloadView
PDM V1.0 Open Access

Abstract

Nucleic acid sequences containing unmethylated CpG dinucleotides that modulate an immune response including stimulating a Th1 pattern of immune activation, cytokine production, NK lytic activity, and B cell proliferation are disclosed. The sequences are also useful a synthetic adjuvant.

Details

Metrics

15 File views/ downloads
12 Record Views